中文名称:
1,1-双十八烷基-3,3,3,3-四甲基吲哚二碳菁高氯酸盐
中文同义词:
1,1`-双十八烷基-3,3,3`,3`-四甲基吲哚二碳花菁高氯酸盐;1,1-双十八烷基-3,3,3,3-四甲基吲哚二碳菁高氯酸盐;细胞膜荧光探针DID;DID(红色细胞膜荧光探针)
英文名称:
1,1-DIOCTADECYL-3,3,3,3-TETRAMETHYLINDODICARBOCYANINE PERCHLORATE
英文同义词:
DiIC18(5) [DiD] [1,1-Dioctadecyl-3,3,3,3-tetraMethylindodicarbocyanine perchlorate];3H-INDOLIUM, 2-[5-(1,3-DIHYDRO-3,3-DIMETHYL-1-OCTADECYL-2H-INDOL-2-YLIDENE)-1,3-PENTADIENYL]-3,3-DIMETHYL-1-OCTADECYL-, PERCHLORATE;DILC18(5);DIIC18(5);DIIC18(5) OIL;DID OIL;DID;DID
相关类别:
荧光素染料;细胞生物学试剂;荧光探针,标记,颗粒和染色;Cyanine
溶解度
Soluble in ethanol, methanol, dimethyl sulfoxide
生物领域应用
Detecting cell lysis,microorganisms,nucleic acids,lipid diffusion in giant unilamellar vesicles,lipid diffusion in phospholipid bilayers,lipids and proteins diffusion in membranes; monitoring cell migration
生物活性
DiD perchlorate 是一种远红色荧光亲脂性花青染料。DiD perchlorate 能快速稳定地与磷脂细胞膜结合,能用于细胞追踪。
体内研究
Two weeks after injection of stained cells, a single, bright, DiD perchlorate (DiD)-positive cells located between 15 to 40 µm from the endosteum is found. Results reveal a progressive appearance of cell clusters of decreased dye intensity, consistent with the partitioning of DiD perchlorate label on cell division.