雷公藤定碱

中文名称:

雷公藤定碱

中文同义词:

雷公藤定碱;雷公藤定;雷公藤碱(雷公藤定碱)

英文名称:

WILFORDINE

英文同义词:

WILFORDINE;8,11-Epoxy-9,12-ethano-11,15-methano-5H,- 11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine- 5,17(18H)-dione,10,13,22,23-tetrakis- (acetyloxy)-12-[(acetyloxy)methyl]-14- (benzoyloxy)-7,8,9,10,12,13,14,15,19,20- decahydro-18,21-dihydroxy-8,18,21- trimethyl-,(8R,9R,10R,11S,12S,13R,14R,15S,- 21S,22S,23R)-;8α-Acetoxy-2-benzoyloxy-2-de(acetoxy)-8-deoxo-26-hydroxyevonimine;(8R,9R,10R,11S,12S,13R,14R,15S,21S,22S,23R)-10,13,22,23-Tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-18,21-dihydroxy-8,18,21-trimethyl-,8,11-epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione;Wilfordin;Wtlfordine;8,11-Epoxy-9,12-ethano-11,15-methano-5H,11H-[1,9]dioxacyclooctadecino[4,3-b]pyridine-5,17(18H)-dione,10,13,22,23-tetrakis(acetyloxy)-12-[(acetyloxy)methyl]-14-(benzoyloxy)-7,8,9,10,12,13,14,15,19,20-decahydro-18,21-dihydroxy-8,18,21-trimethyl-,(8R,9R,10R

CAS号:

37239-51-3

分子式:

C43H49NO19

分子量:

883.85

EINECS号:

相关类别:

植提;中药对照品;标准品;植提标准品;雷公藤系列;植物提取物;标准品 -中药标准品

Mol文件:

37239-51-3.mol

沸点 

895.5±65.0 °C(Predicted)

密度 

1.44±0.1 g/cm3(Predicted)

酸度系数(pKa)

11.63±0.70(Predicted)

概述

雷公藤中主要有效活性成分是雷公藤生物碱、二萜以及三萜类化合物。雷公藤吉碱(wilforgine)、雷公藤次碱(wilforine)、雷公藤定碱(wilfordine)、雷公藤春碱(wilfortrine)最早是从雷公藤根里分离出来的。

用途

雷公藤是中国一种传统中药，雷公藤定碱是其活性成分，具有治疗免疫疾病、抗炎、抗生育等效果。