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环黄芪醇

中文名称:
环黄芪醇
中文同义词:
三萜环黄氏醇;环黄芪醇;环黄芪宁;CYCLOASTRAGENOL 环黄芪醇;环黄芪醇(三萜环黄氏醇);环黄芪醇,CYCLOASTRAGENOL;环黄芪醇, >98%;环黄芪醇对照品,
英文名称:
cycloastragenol
英文同义词:
cycloastragenol;(3b,5ξ,6a,9ξ,10ξ,16b,17ξ,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;(3beta,6alpha,16beta,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;(3b,6a,16b,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;Cyclogalagenin;Cyclogalegenin;Cyclogalegigenin;Cyclogalgeginin
CAS号:
84605-18-5
分子式:
C30H50O5
分子量:
490.71
EINECS号:
 
相关类别:
优势产品;医药原料;植提标准品;对照品;中药对照品;标准品;对照品,标准品;植物提取物;chemical reagent;植物成分单体;分析试剂标准品;原料;标准品-中药标准品;有机原料;标准品 -中药标准品;分析试剂-标准品;标准品,对照品;分析试剂标准品;palnt extract;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol文件:
84605-18-5.mol
 
 
沸点 
617.2±55.0 °C(Predicted)
密度 
1.20
酸度系数(pKa)
14.57±0.29(Predicted)
生物活性
Cycloastragenol 是一种天然的四环三萜类化合物,在筛选黄芪提取物时鉴定出具有抗衰老活性。Cycloastragenol 是一种有效的端粒酶 (telomerase) 激活剂。Cycloastragenol 还具有其他药理作用,包括抗炎和抗氧化特性。
靶点
Target Value telomerase ()
Target
Value
telomerase ()
 
体外研究
Cycloastragenol (0-10 µM; 3-6 days) increases cell growth compared to the vehicle control in HEK cultures. Cycloastragenol (0.3 µM; 5-90 mins) induces CREB phosphorylation in primary cortical neurons, total CREB expression is unaltered by CAG in both cell type.Cycloastragenol (3 µM; 6-48 hours) may promotes prosurvival signaling in neurons, increases tert mRNA expression, exhibits increased bcl2 mRNA expression. Cell Viability Assay Cell Line: HEK cells Concentration: 1 µM, 3 µM, 10 µM Incubation Time: 3-6 days Result: Doubled the cell growth at 6 days. Western Blot Analysis Cell Line: Neuronal cells Concentration: 0-3 µM Incubation Time: 5 mins, 15 mins, 30 mins, 90 mins Result: Suggested that CAG induces CREB activation in neuronal cells. Western Blot Analysis Cell Line: Neuronal cells Concentration: 0-3 µM Incubation Time: 6-48 hours Result: Increased tert, bcl2 mRNA expression.
Cell Line:
HEK cells
Concentration:
1 µM, 3 µM, 10 µM
Incubation Time:
3-6 days
Result:
Doubled the cell growth at 6 days.
Cell Line:
Neuronal cells
Concentration:
0-3 µM
Incubation Time:
5 mins, 15 mins, 30 mins, 90 mins
Result:
Suggested that CAG induces CREB activation in neuronal cells.
Cell Line:
Neuronal cells
Concentration:
0-3 µM
Incubation Time:
6-48 hours
Result:
Increased tert, bcl2 mRNA expression.
化学性质 
来源于豆科植物蒙古黄芪 Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.)Hsiao干燥根
用途 
用于含量测定/鉴定/药理实验等。
CAS号:84605-18-5
规   格:10g/20g/100g/1kg
价   格:请咨询卖家
数   量:
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英文名:cycloastragenol
外观:
纯度:请咨询卖家
分子式:C30H50O5
分子量:490.71
最小起售量:10g/20g/100g/1kg
中文名称:
环黄芪醇
中文同义词:
三萜环黄氏醇;环黄芪醇;环黄芪宁;CYCLOASTRAGENOL 环黄芪醇;环黄芪醇(三萜环黄氏醇);环黄芪醇,CYCLOASTRAGENOL;环黄芪醇, >98%;环黄芪醇对照品,
英文名称:
cycloastragenol
英文同义词:
cycloastragenol;(3b,5ξ,6a,9ξ,10ξ,16b,17ξ,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;(3beta,6alpha,16beta,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;(3b,6a,16b,24R)-20,24-Epoxy-9,19-cyclolanostane-3,6,16,25-tetrol;Cyclogalagenin;Cyclogalegenin;Cyclogalegigenin;Cyclogalgeginin
CAS号:
84605-18-5
分子式:
C30H50O5
分子量:
490.71
EINECS号:
 
相关类别:
优势产品;医药原料;植提标准品;对照品;中药对照品;标准品;对照品,标准品;植物提取物;chemical reagent;植物成分单体;分析试剂标准品;原料;标准品-中药标准品;有机原料;标准品 -中药标准品;分析试剂-标准品;标准品,对照品;分析试剂标准品;palnt extract;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
Mol文件:
84605-18-5.mol
 
 
沸点 
617.2±55.0 °C(Predicted)
密度 
1.20
酸度系数(pKa)
14.57±0.29(Predicted)
生物活性
Cycloastragenol 是一种天然的四环三萜类化合物,在筛选黄芪提取物时鉴定出具有抗衰老活性。Cycloastragenol 是一种有效的端粒酶 (telomerase) 激活剂。Cycloastragenol 还具有其他药理作用,包括抗炎和抗氧化特性。
靶点
Target Value telomerase ()
Target
Value
telomerase ()
 
体外研究
Cycloastragenol (0-10 µM; 3-6 days) increases cell growth compared to the vehicle control in HEK cultures. Cycloastragenol (0.3 µM; 5-90 mins) induces CREB phosphorylation in primary cortical neurons, total CREB expression is unaltered by CAG in both cell type.Cycloastragenol (3 µM; 6-48 hours) may promotes prosurvival signaling in neurons, increases tert mRNA expression, exhibits increased bcl2 mRNA expression. Cell Viability Assay Cell Line: HEK cells Concentration: 1 µM, 3 µM, 10 µM Incubation Time: 3-6 days Result: Doubled the cell growth at 6 days. Western Blot Analysis Cell Line: Neuronal cells Concentration: 0-3 µM Incubation Time: 5 mins, 15 mins, 30 mins, 90 mins Result: Suggested that CAG induces CREB activation in neuronal cells. Western Blot Analysis Cell Line: Neuronal cells Concentration: 0-3 µM Incubation Time: 6-48 hours Result: Increased tert, bcl2 mRNA expression.
Cell Line:
HEK cells
Concentration:
1 µM, 3 µM, 10 µM
Incubation Time:
3-6 days
Result:
Doubled the cell growth at 6 days.
Cell Line:
Neuronal cells
Concentration:
0-3 µM
Incubation Time:
5 mins, 15 mins, 30 mins, 90 mins
Result:
Suggested that CAG induces CREB activation in neuronal cells.
Cell Line:
Neuronal cells
Concentration:
0-3 µM
Incubation Time:
6-48 hours
Result:
Increased tert, bcl2 mRNA expression.
化学性质 
来源于豆科植物蒙古黄芪 Astragalus membranaceus (Fisch.) Bge. var. mongholicus (Bge.)Hsiao干燥根
用途 
用于含量测定/鉴定/药理实验等。
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