番泻甙元B

中文名称:

番泻甙元B

中文同义词:

番泻甙元B;番泻苷元B;番泻叶甙B

英文名称:

SENNIDINE B

英文同义词:

SENNIDINE B;(R*,S*)-9,9,10,10-tetrahydro-4,4,5,5-tetrahydroxy-10,10-dioxo[9,9-bianthracene]-2,2-dicarboxylic acid;9-(2-carboxy-4,5-dihydroxy-10-oxo-9H-anthracen-9-yl)-4,5-dihydroxy-10-oxo-9H-anthracene-2-carboxylic acid;Sennidin B;SENNIDINE B hplc;9-(2-carboxy-4,5-dihydroxy-10-keto-9H-anthracen-9-yl)-4,5-dihydroxy-10-keto-9H-anthracene-2-carboxylic acid;[9,9-Bianthracene]-2,2-dicarboxylicacid, 9,9,10,10-tetrahydro-4,4,5,5-tetrahydroxy-10,10-dioxo-,(9R,9S)-rel-

CAS号:

517-44-2

分子式:

C30H18O10

分子量:

538.46

EINECS号:

208-239-4

相关类别:

标准品;植物提取物;标准品-中药标准品;标准品 -中药标准品;对照品;chemical reagent;pharmaceutical intermediate;Anthraquinones, Hydroquinones and Quinones;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract

Mol文件:

517-44-2.mol

密度 

1.695±0.06 g/cm3 (20 ºC 760 Torr)

生物活性

Sennidin B可从Cassia angustifolia 分离得到，是Sennidin A 的异构体，活性比Sennidin A 低。Sennidin A，能够抑制HCV NS3 解旋酶，其 IC50 值为0.8 μM。Sennidin A诱导Akt和葡萄糖转运蛋白4 (GLUT4) 的磷酸化。Sennidin A刺激葡萄糖掺入。

靶点

GLUT4 Akt HCV NS3

GLUT4

Akt

危险类别码 

22

安全说明 

22-45