桑皮酮A

中文名称:

桑皮酮A

中文同义词:

桑黄酮 A;桑皮酮A;桑皮酮A标准品;桑皮酮A对照品

英文名称:

5,7-Dihydroxy-2-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one

英文同义词:

5,7-Dihydroxy-2-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-(3-methyl-2-butenyl)-4H-1-benzopyran-4-one;5,7-Dihydroxy-2-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-(3-methyl-2-buten-1-yl)-4H-1-benzopyran-4-one;Kuwanon A;4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(5-hydroxy-2,2-dimethyl-2H-1-benzopyran-8-yl)-3-(3-methyl-2-buten-1-yl)-

CAS号:

62949-77-3

分子式:

C25H24O6

分子量:

420.45

EINECS号:

相关类别:

分析试剂标准品;标准品;对照品;标准品，对照品

Mol文件:

62949-77-3.mol

熔点 

176-177 °C

沸点 

637.3±55.0 °C(Predicted)

密度 

1.303±0.06 g/cm3(Predicted)

储存条件 

Sealed in dry,2-8°C

酸度系数(pKa)

6.60±0.40(Predicted)

生物活性

Kuwanon A是从桑树 (Morus alba L.) 的根皮中分离的的黄酮衍生物，抑制一氧化氮产生的IC50值为10.5 μM。

靶点

IC50: 10.5 μM (nitric oxide)

体外研究

Kuwanon A shows significant inhibitory activity towards the differentiation of 3T3-L1 adipocytes with TG inhibition values of 47.1%. Kuwanon A also shows significant nitric oxide (NO) production inhibitory effects in RAW264.7 cells with an IC 50 of 10.5 μM.