alpha-香附酮

中文名称:

alpha-香附酮

中文同义词:

α-香附酮;(4aS,7R)-1,4a-二甲基-7-丙-1-烯-2-基-3,4,5,6,7,8-六氢萘-2-酮;Α-香附酮(标准品);Α-CYPERONE Α-香附酮;A-香附酮--液体;A-香附酮;alpha-香附酮;Α-香附酮, >99%

英文名称:

alpha-Cyperone

英文同义词:

alpha-Cyperone (α-Cyperone);α-Cyperone 473-08-5;alpha-Cyperone, >99%;α-cyperon;α-cyperone;(4aS-cis)-4,4a,5,6,7,8-Hexahydro-1,4a-dimethyl-7-(1-methylethenyl)-2(3H)-naphthalenone;A-CYPERONE;(4aS,7R)-1,4a-Dimethyl-7-prop-1-en-2-yl-3,4,5,6,7,8-hexahydronaphthalen-2-one

CAS号:

473-08-5

分子式:

C15H22O

分子量:

218.33

EINECS号:

相关类别:

标准品-对照品;标准品-中药标准品;植物药;中药对照品;标准品;对照品,标准品;植物提取物;chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract;对照品;可定制;标准品 -中药标准品;标准品，对照品

Mol文件:

473-08-5.mol

熔点 

232 °C

沸点 

177 °C(Press: 20 Torr)

密度 

0.9946 g/cm3(Temp: 25 °C)

储存条件 

Sealed in dry,Store in freezer, under -20°C

简介

alpha-香附酮为黄色液体，易溶于甲醇、水，来源于香附，益智仁，莎草科植物香附(莎草) Cyperus rotundus L. 的根茎。  

生物活性

α-Cyperone (alpha-cyperone) 是香附子Cyperus rotundus的主要活性成分，表现出了如抗毒力、抗原毒性和抗菌活性等生物活性。α-Cyperone (alpha-cyperone) 与COX-2、IL-6、Nck-2、Cdc42 和 Rac1 的表达下调有关。

靶点

Human Endogenous Metabolite

Human Endogenous Metabolite

体外研究

The anti-inflammatory activity of alpha-Cyperone (α-Cyperone) is associated with the down-regulation of COX-2 and IL-6 via the negative regulation of the NFκB pathway in LPS-stimulated RAW 264.7 cells. alpha-Cyperone (α-Cyperone) binds and interacts with tubulin and is capable of distinctly destabilizing microtubule polymerization. The effect of this interaction could result in reduction of inflammation which would be highly beneficial for treatment of inflammatory diseases such as AD. One microliter of alpha-Cyperone was dissolved in DMSO (1:1 v/v) and it was further diluted in double distilled water (ddH2O) to a final volume of 20 microliter.

化学性质 

黄色液体，易溶于甲醇、水，来源于香附，益智仁，莎草科植物香附(莎草) Cyperus rotundus L. 的根茎。

用途 

α-香附酮具有解热镇痛的作用。

用途 

用于含量测定/鉴定/药理实验等 药理药效:疏肝解郁，养血调经止痛

安全说明 

24/25

海关编码 

29143990