英文名称:
CalciuM polycarbophil
英文同义词:
Polycarbophil;CARBOPOLEX55;Carbofil;Policarbofila;polycarbophil calcium;CALCIUM POLYCARBOPHIL;Policarbofila [inn-spanish];Polyacrylic acid calcium salt cross-linked with divinyl glycol
相关类别:
其他原料;医药 水性腹泻;医药原料;水性腹泻;原料;医用原料;医药、农药及染料中间体;化工原料
溶解度
Polycarbophil polymers do not dissolve in water but can swell in water to around 1000 times their original volume (and ten times their original diameter) to form gels when exposed to a pH environment above 4–6. Since the pKa of these polymers is 6.0±0.5, the carboxylate groups on the polymer backbone ionize, resulting in electrostatic repulsion between the negative particles, which extends the molecule, adding to the swelling of the polymer.
概述
聚卡波非钙片的活性成分是二乙烯基乙二醇交联丙烯酸共聚物的钙盐,为亲水性树脂,是一种吸水性的高分子聚合物。
用途
聚卡波非钙(calciumpolycarbophil)最早由美国雅培公司开发,在欧美、日本已广泛使用,用于IBS及各种原因便秘症状的缓解。