中文名称:

(DES-ARG9)-BRADYKININ

中文同义词:

血管舒缓激肽片段1-8,醋酸盐水合物;DES-ARG9]-缓激肽;脱精氨酸9缓激肽

英文名称:

ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE

英文同义词:

RPPGFSPF;(DES-ARG9)-BRADYKININ;H-ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE-OH;ARG-PRO-PRO-GLY-PHE-SER-PRO-PHE;BRADYKININ [DES-ARG9];des-arg(9)-bradykini;bradykinin fragment 1-8;[des-arg9]-bradykinin acetate hydrate

CAS号:

15958-92-6

分子式:

C44H61N11O10

分子量:

904.02

EINECS号:

相关类别:

细胞信号和神经生物学;Peptide

Mol文件:

15958-92-6.mol

密度 

1.47±0.1 g/cm3(Predicted)

储存条件 

−20°C

酸度系数(pKa)

3.56±0.10(Predicted)

生物活性

[Des-Arg9]-Bradykinin 是一种Bradykinin (B1) 受体激动剂，对 B1 受体选择性比B2 受体高。

靶点

Bradykinin (B 1 ) receptor

体外研究

The B 2 receptor mediates the action of bradykinin (BK) and lysyl-bradykinin (Lys-BK), the first set of bioactive kinins formed in response to injury from kininogen precursors through the actions of plasma and tissue kallikreins, whereas the B 1 receptor mediates the action of [Des-Arg 9 ]-Bradykinin (des-Arg 9 -BK) and Lys-des-Arg Arg 9 -BK, the second set of bioactive kinins formed through the actions of carboxypeptidases on BK and Lys-BK, respectively.

WGK Germany 

3