氯胺-T 三水合物
中文名称:
氯胺-T 三水合物
中文同义词:
三水合氯铵-T;氯铵-T三水;氯胺T钠;氯胺T,三水;氯胺T三水合物;亚明T;三水合氯胺T;氯胺T钠三水合物
英文名称:
Chloramine-T trihydrate
英文同义词:
CHLORAMINE T 3-HYDRATE;Chloramine-T trihydrate, ACS, 98.0-103.0%;Chloroamine t trihydrate;Benzenesulfonamide, N-chloro-4-methyl-, sodium salt, trihydrate;chloramine-t trihydrate, acs;CHLORAMINE T REAGENT (ACS);N-Chloro-p-toluenesulfonamide sodium salt, Chloraminum;Chloramine-T trihydrate,97+%
CAS号:
7080-50-4
分子式:
C7H11ClNNaO3S
分子量:
247.67
EINECS号:
615-172-8
相关类别:
氧化;生化试剂;有机化学;消毒剂;卤代物;其他生化试剂;通用试剂;Chlorination;Classes of Metal Compounds;Halogenation;Na (Sodium) Compounds (excluding simple sodium salts);Oxidation;Synthetic Organic Chemistry;Typical Metal Compounds;合成试剂;有机化工原料;消杀
Mol文件:
7080-50-4.mol
熔点
167-170 °C(lit.)
密度
1.43
闪点
92 °C
储存条件
Store at +2°C to +8°C.
溶解度
H2O: passes test
酸度系数(pKa)
pK1:4.54(+1) (25°C)
形态
Crystalline Powder
颜色
White to off-white
气味 (Odor)
Chlorine like
PH值
8-10 (50g/l, H2O, 20℃)
酸碱指示剂变色ph值范围
8 - 10
水溶解性
Soluble in water and ethyl alcohol. Insoluble in benzene and ethers.
敏感性
Moisture Sensitive
Merck
14,2075
BRN
3924168
CAS 数据库
7080-50-4(CAS DataBase Reference)
生物活性
Tosylchloramide sodium trihydrate (Chloramine T sodium trihydrate) 是广泛厨房，实验室和医院的消毒剂。也用作空气清新剂和除臭剂中的杀生物剂。
体外研究
Gram-positive growth is reduced by 95% to 100% after tosylchloramide treatment, regardless of dose, with or without serum. E coli (gram-negative; with/without serum) is reduced 94% to 100% at antiseptic concentrations of 300 and 400 ppm. At 200 ppm, E coli growth is fully inhibited without serum present and by 50% with serum. At 100 and 200 ppm, cell viability remains greater than 90% under all experimental conditions. A 300-ppm, 3-minute exposure to tosylchloramide results in cell viability of up to 70%, with longer exposures producing lower viabilities. Serum does not affect cell viability in any condition.
体内研究
A dose-dependently significant DNA damage in the rat tissues and inflammation is histopathologically noted around the terminal airways of the lung in both male and female rats. The 24-h exposure to 50 mg/L of chloramine-T is toxic for crayfish and leads to substantial loss of energy that became apparent during subsequently conducted physical stress. Tosylchloramide may potentiate the toxicity of many xenobiotics via metabolic activation and/or accumulation of reactive metabolites. The activities of CYP2E1, CYP1A1/2 CYP2B1/2, CYP3A4 and CYP4A1/2 enzymes significantly increase after treatment with 2.50, 5 and 10 mg/kg bw/day tosylchloramide, in a dose-dependent manner. This effect is not observed after tosylchloramide treatment at dose of 1.25 mg/kg bw/day.
用途
容量分析中用作碘及次氯酸盐标准溶液的代用品，检定溴酸盐和卤素，测定碘化物、铊和锡、用作供给氯的试剂，消毒剂，医药(防腐剂)。
危险品标志
C
危险类别码
22-31-34-42
安全说明
22-26-36/37/39-45-7
危险品运输编号
UN 3263 8/PG 3
WGK Germany
2
RTECS号
XT5616800
TSCA
Yes
HazardClass
8
PackingGroup
III
海关编码
29350090
毒性
LD50 orally in Rabbit: 935 mg/kg
