CORONALOLIC ACID

中文名称:

CORONALOLIC ACID

中文同义词:

英文名称:

Coronalolic acid

英文同义词:

Coronalolic acid;Coronalonic acid;1H-Cyclopenta[a]cyclopropa[e]naphthalene-3a(4H)-propanoic acid, 7-[(1R,4E)-1,5-dimethyl-6-oxo-4-hexen-1-yl]decahydro-3-[1-(hydroxymethyl)ethenyl]-6a,9a-dimethyl-, (3R,3aR,4aS,6aR,7R,9aS,9bS)-

CAS号:

268214-52-4

分子式:

C30H46O4

分子量:

470.68

EINECS号:

相关类别:

植物提取物;三萜

Mol文件:

268214-52-4.mol

生物活性

Coronalolic acid 是 Garden 子叶顶芽提取出来的，可以抑制 TNF-α 诱导的 NF-κB 活性和 NO 产生。

靶点

NF-κB

NF-κB

体外研究

Coronalolic acid has an inhibition effect against the TNF-α-induced NF-κB activity and NO production with IC 50 s of 15.4 μM and 15.0 μM in LPS-stimulated RAW 264.7 cells, respectively.