连翘脂素

中文名称:

连翘脂素

中文同义词:

连翘甙元;连翘素;连翘苷元;连翘脂素,连翘苷元;连翘脂素, >98%;连翘脂素标准品;连翘脂素对照品

英文名称:

(+)-SYLVATESMIN

英文同义词:

Philligenin;Phillygenin, >98%;4-[(3S,3aR,6R,6aR)-6-(3,4-dimethoxyphenyl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-3-yl]-2-methoxyphenol;(+)-Phillygenin;(1S)-1β-(3-Methoxy-4-hydroxyphenyl)-4α-(3,4-dimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan;(1S,3aβ,6aβ)-1β-(3-Methoxy-4-hydroxyphenyl)-4α-(3,4-dimethoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan;4-[[(1S)-4α-(3,4-Dimethoxyphenyl)-3aβ,4,6,6aβ-tetrahydro-1H,3H-furo[3,4-c]furan]-1β-yl]-2-methoxyphenol;Phillygenin

CAS号:

487-39-8

分子式:

C21H24O6

分子量:

372.41

EINECS号:

相关类别:

分析试剂标准品;木脂素;标准品;连翘系列;植物提取物;对照品;Miscellaneous Natural Products;标准品-对照品;对照品-中药对照品;标准品 -中药标准品;标准品，对照品

Mol文件:

487-39-8.mol

熔点 

133℃

沸点 

534.9±50.0 °C(Predicted)

密度 

1.225

储存条件 

Keep in dark place,Sealed in dry,2-8°C

酸度系数(pKa)

9.84±0.35(Predicted)

生物活性

Phillygenin是连翘的一种活性组分，有很多的药用价值，例如抗氧化剂，降血脂，抑制低密度脂蛋白氧化。

体外研究

1) Phillygenin shows a greater inhibition on mouse B16 melanoma cells potential than vincristine. 2) phillygenin had notable scavenging activity against DPPH, ABTS radicals, as well as potent reducing power in FRAP assay.

体内研究

The reference for rat is 5.6 mg/m l ( i.v).

化学性质 

白色结晶性粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于连翘。

用途 

用于含量测定/鉴定/药理实验等。