酚红钠

中文名称:

酚红钠

中文同义词:

酚红钠盐, ACS;酚红钠盐, 0.02%水溶液;酚红钠盐;水溶性酚红钠盐,酚红钠;酚磺酞 钠盐;苯酚红, SODIUM SALT;苯酚红钠, ACS;苯酚红钠, 0.02% W/V AQ. SOLN.

英文名称:

Phenol Red sodium salt

英文同义词:

SODIUM PHENOL RED;PHENOLSULFONEPHTHALEIN MONOSODIUM SALT;PHENOLSULFONEPHTHALEIN SODIUM SALT;PHENOLSULFONPHTHALEIN NA-SALT;PHENOLSULFONPHTHALEIN, SODIUM SALT;PHENOLSULFONPHTHALEIN;PHENOLSULPHONEPHTHALEIN SODIUM SALT;PHENOL RED, WATER SOLUBLE

CAS号:

34487-61-1

分子式:

C19H13NaO5S

分子量:

376.36

EINECS号:

252-057-8

相关类别:

化学试剂;生化试剂-色素类;医药中间体;标准品和标准物质;血液学和组织学;生化试剂;染色剂和染料;色素类;酸碱指示剂;Analytical Chemistry;Indicator (pH);pH Indicators;有机化学;Sulfonephthalein;毛发中间体;分析试剂-染料中间体

Mol文件:

34487-61-1.mol

熔点 

285 °C (dec.)(lit.)

沸点 

285 °C

密度 

0.972

储存条件 

room temp

溶解度 

H2O: clarity passes test

酸度系数(pKa)

7.69, 7.9, 1.3(at 25℃)

形态

Shiny Powder

颜色

White

气味 (Odor)

Odorless

酸碱指示剂变色ph值范围

Yellow (6.8) to red (8.4)

水溶解性 

soluble

最大波长(λmax)

423nm, 557nm

Merck 

14,7247

BRN 

6260026

稳定性

Stable. Incompatible with strong oxidizing agents.

主要应用

Sensor, optical device, paints, sterilization process, fertilizer, detecting viable cells, gastrointestinal mucosa, antibacterial agent, drugs, pharmacology

CAS 数据库

34487-61-1(CAS DataBase Reference)

EPA化学物质信息

Phenol, 4,4-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-, monosodium salt (34487-61-1)

生物活性

Phenol Red sodium salt (Phenolsulfonephthalein sodium salt) 在组织培养基中普遍用作pH指示剂，范围从6.8(黄色)到8.2(红色)。Phenol Red sodium salt 可与MCF-7人乳腺癌细胞的 estrogen receptor 向结合。

靶点

Target Value Estrogen Receptor ()

Target

Value

Estrogen Receptor ()

体外研究

Phenol Red sodium salt is commonly employed as a cell tissue culture pH marker. Under normal conditions, phenol red added to the growth medium will have a pink-red color. Dying cells or overgrowth of contaminants will cause a change in pH resulting in a change in indicator color. Phenol red bears a structural resemblance to some nonsteroidal estrogens and has significant estrogenic activity at the concentrations (15-45 μM) at which it is found in tissue culture media. Phenol red binds to the estrogen receptor of MCF-7 human breast cancer cells and stimulates the proliferation of estrogen receptor-positive MCF-7 breast cancer cells in a dose-dependent manner but has no effect on the growth of estrogen receptor-negative MDA-MB-231 breast cancer cells. Phenol red is a simple, rapid and inexpensive method for the measurement of hydrogen peroxide produced by cells in culture. The assay is based on the horseradish peroxidase-mediated oxidation of phenol red by hydrogen peroxide which results in the formation of a compound demonstrating increased absorbance at 610 nm.

用途 

用作酸碱指示剂

危险品标志 

Xi,C

危险类别码 

36/37/38-34

安全说明 

26-36-37/39-45-36/37/39-27

WGK Germany 

3

TSCA 

Yes

海关编码 

29349990