奥美沙坦酯杂质I

中文名称:

奥美沙坦酯杂质I

中文同义词:

奥美沙坦酯杂质C;奥美沙坦杂质I;奥美沙坦EP杂质C;奥美沙坦酯杂质I;奥美沙坦酯杂质C (EP);美沙坦酯杂质C;奥美沙坦酯EP杂质C;4-(1-甲基乙烯)-2-丙基-1-[[2-(2H-四ZOL-5-基)[1,1-联苯]-4-基]甲基]-1H-咪唑-5-羧酸(5-甲基-2-氧代-1,3-二氧代L-4-基)甲酯

英文名称:

Olmesartan medoxomil impurity I

英文同义词:

(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 1-((2-(1H-tetrazol-5-yl)-[1,1-biphenyl]-4-yl)methyl)-4-(prop-1-en-2-yl)-2-propyl-1H-imidazole-5-carboxylate;4-(1-Methylethenyl)-2-propyl-1-[[2-(2H-tetrazol-5-yl)[1,1-biphenyl]-4-yl]Methyl]-;4-(1-methylethenyl)-2-propyl-1-[[2-(2H-tetrazol-5-yl)[1,1-biphenyl]-4-yl]methyl]-1H-Imidazole-5-carboxylic acid(5-methyl-2-oxo-1,3-dioxol-4-yl)methy;Olmesartan Medoxomil Dehydro;Olmesartan Medoxomil EP Impurity C;Olmesartan Medoxomil EP Impurity C (Dehydro Impurity), RNH-6373;4-(1-Methylethenyl)-2-propyl-1-[[2-(2H-tetrazol-5-yl)[1,1-biphenyl]-4-yl]methyl]-1H-Imidazole-5-carboxylic acid(5-methyl-2-oxo-1,3-dioxol-4-yl)methylester;Olmesartan Medoxomil-3

CAS号:

879562-26-2

分子式:

C29H28N6O5

分子量:

540.57

EINECS号:

相关类别:

氨基酸;杂质对照品;医药原料;Aromatics;Bases Related Reagents;Heterocycles;Intermediates;Intermediates Fine Chemicals;Nucleotides;Pharmaceuticals

Mol文件:

879562-26-2.mol

沸点 

774.0±70.0 °C(Predicted)

密度 

1.34±0.1 g/cm3(Predicted)

酸度系数(pKa)

4.16±0.10(Predicted)

生物活性

Olmesartan medoxomil impurity C 是Olmesartan medoxomil 的杂质。Olmesartan medoxomil 是一种有效的选择性的 血管紧张素 (angiotensin AT1) 受体抑制剂，IC50 为 66.2 μM。