棘白菌素

中文名称:

棘白菌素

中文同义词:

棘白菌素

英文名称:

Rezafungin

英文同义词:

Rezafungin;SP-3025

CAS号:

1396640-59-7

分子式:

C63H85N8O17

分子量:

0

EINECS号:

相关类别:

Mol文件:

Mol File

生物活性

Rezafungin (Biafungin) 是下一代，广谱且持久的棘皮菌素。Rezafungin 显示对念珠菌，曲霉和肺孢子菌具有有效的抗真菌活性。

体内研究

Rezafungin (Biafungin) shows potent in vivo efficacy as prophylaxis against Pneumocystis in an in vivo mouse infection model. Animal Model: C3H/HeN mice Dosage: 1 mg/kg Administration: Intraperitoneal injection; once daily for 6 days Result: Significantly reduced nuclei and asci burdens.

Animal Model:

C3H/HeN mice

Dosage:

1 mg/kg

Administration:

Intraperitoneal injection; once daily for 6 days

Result:

Significantly reduced nuclei and asci burdens.