2-甲基-2-丙基-4-(6 - {[8-环戊基-5-甲基-7-氧代-6-(1-丁氧乙烯基)-7,8-二氢吡啶并[2,3

中文名称:

2-甲基-2-丙基-4-(6 - {[8-环戊基-5-甲基-7-氧代-6-(1-丁氧乙烯基)-7,8-二氢吡啶并[2,3-D]嘧啶-2-基]氨基} -3-吡啶基)-1-哌嗪甲酸

中文同义词:

帕布西利布-中间体7;4-(6-((6-(1-丁氧基乙烯基C-8-环戊基-5-甲基-7-氧代-7,8-二氢吡啶并[2,3-D]嘧啶-2-基C氨基)吡啶-3-基)哌嗪-1-甲酸叔丁酯;2-甲基-2-丙基-4-(6 - {[8-环戊基-5-甲基-7-氧代-6-(1-丁氧乙烯基)-7,8-二氢吡啶并[2,3-D]嘧啶-2-基]氨基} -3-吡啶基)-1-哌嗪甲酸;4-(6-(8-环戊基-6-(1-正丁氧基乙烯基)-7,8-二氢-5-甲基-7-氧代吡啶并[2,3-D]嘧啶-2-基氨基)吡啶-3-基)哌嗪-1-羧酸叔丁酯;2-甲基-2-丙基-4-(6-{[8-环戊基-5-甲基-7-氧代-6-(1-丁氧乙烯基)-7,8-二;帕布西利布中间体2;帕布昔利布标准品017;帕布昔利布中间体2

英文名称:

tert-butyl 4-(6-(8-cyclopentyl-5-Methyl-7-oxo-6-(1-propoxyvinyl)-7,8-dihydropyrido[2,3-d]pyriMidin-2-ylaMino)pyridin-3-yl)piperazine-1-carboxylate

英文同义词:

Palbociclib Impurity 73;Palbociclib impurity 19/Tert-butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate;tert-butyl 4-(6-(8-cyclopentyl-5-Methyl-7-oxo-6-(1-propoxyvinyl)-7,8-dihydropyrido[2,3-d]pyriMidin-2-ylaMino)pyridin-3-yl)piperazine-1-carboxylate;Palbociclib INT;tert-butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate;4-[6-[[6-(1-Butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl]amino]pyridin-3-yl]piperazine-1-carboxylic acid tert-butyl ester;tert-butyl 4-(6-(8-cyclopentyl-5-Methyl-7-oxo-6-(1-propoxyvinyl)-7,8-dihydropyrido[2,3-d]pyriMidin-2;Palbociclib-017

CAS号:

866084-31-3

分子式:

C33H45N7O4

分子量:

603.75

EINECS号:

相关类别:

对照品-杂质对照品;帕博西尼中间体;杂质对照品;Anticancer

Mol文件:

866084-31-3.mol

沸点 

764.2±70.0 °C(Predicted)

密度 

1.224±0.06 g/cm3(Predicted)

储存条件 

Keep in dark place,Sealed in dry,2-8°C

酸度系数(pKa)

5.24±0.10(Predicted)

用途

2-甲基-2-丙基-4-(6 - {[8-环戊基-5-甲基-7-氧代-6-(1-丁氧乙烯基)-7,8-二氢吡啶并[2,3-D]嘧啶-2-基]氨基} -3-吡啶基)-1-哌嗪甲酸是用于乳腺癌治疗的高选择性CDK 4/6可逆抑制剂帕博西林商业开发的中间体。