非布索坦相关物质

中文名称:

非布索坦相关物质

中文同义词:

非布司他杂质12;非布司他杂质D;非布索坦杂质A;非布索坦相关物质;2-[3-(氨基羰基)-4-(2-甲基丙氧基)苯基]-4-甲基-5-噻唑羧酸;非布索坦杂质121;非布索坦酰胺杂质;非布司他酰胺杂质

英文名称:

2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid

英文同义词:

2-[3-(AMinocarbonyl)-4-(2-Methylpropoxy)phenyl]-4-Methyl-5-thiazolecarboxylic Acid;Febuxostat Impurity 4 (A);Febuxostat Related Compound (Febuxostat Impurity 4 );Febuxostat-1;Febuxostat Impurity 10/Febuxostat Amide Impurity/2-(3-carbamoyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid;2-[3-carbamoyl-4-(2-methylpropoxy)phenyl]-4-methyl-5-thiazole carboxylic acid;Febuxostat Amide;Febuxostat Related CoMpound

CAS号:

1239233-86-3

分子式:

C16H18N2O4S

分子量:

334.39

EINECS号:

相关类别:

标准品;对照品-杂质对照品;氨基酸衍生化合物;非布索坦杂质;杂质对照品;Heterocycles, Impurities, Inhibitors, Pharmaceuticals, Intermediates Fine Chemicals

Mol文件:

1239233-86-3.mol

沸点 

538.9±60.0 °C(Predicted)

密度 

1.291±0.06 g/cm3(Predicted)

酸度系数(pKa)

1.22±0.37(Predicted)

生物活性

Febuxostat amide impurity 是 Febuxostat 一种杂质。Febuxostat 是选择性黄嘌呤氧化酶 (XO) 抑制剂，Ki 为 0.6 nM。