alpha-酮戊二酸钙盐

中文名称:

alpha-酮戊二酸钙盐

中文同义词:

2-氧代-1,5-戊二酸钙盐;alpha-酮戊二酸钙盐;Α-酮戊二酸钙盐;阿尔法酮戊二酸钙;阿法酮戊二酸钙盐;酮戊二酸钙

英文名称:

Calcium 2-oxoglutarate

英文同义词:

CALCIUM ALPHA-KETOGLUTARATE MONOHYDRATE;ALPHA-KETOGLUTARATE CALCIUM MONOHYDRATE;A-KETOGLUTARIC ACID, CALCIUM SALT, MONOHYDRATE;Calcium 2-oxoglutarate;Pentanedioic Acid ,2-oxo-,Calcium Salt;α-Ketoglutaric acid calcium salt;2-Oxopentanedioic acid calcium salt;Calcium 2-oxopentanedioate

CAS号:

71686-01-6

分子式:

C5H8CaO5

分子量:

188.19

EINECS号:

275-843-2

相关类别:

产品;医药原料;化工原料

Mol文件:

71686-01-6.mol

CAS 数据库

71686-01-6(CAS DataBase Reference)

生物活性

Calcium 2-oxoglutarate 是 Krebs 循环中 ATP 或 GTP 产生的中间体。Calcium 2-oxoglutarate 还充当氮同化反应的主要碳骨架。Calcium 2-oxoglutarate 是酪氨酸酶 (tyrosinase) 的可逆抑制剂 (IC50=15 mM)。

靶点

Tyrosinase 15 mM (IC 50 ) Human Endogenous Metabolite

Tyrosinase 15 mM (IC 50 )

Human Endogenous Metabolite

体外研究

Calcium 2-oxoglutarate has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning. Calcium 2-oxoglutarate acts as precursor for the synthesis of amino acids and nucleotides.