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中文名称:

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中文同义词:

反式-NED-19

英文名称:

trans-Ned 19

英文同义词:

trans-Ned 19;(1R,3S)-1-[3-[[4-(2-Fluorophenyl)-1-piperazinyl]Methyl]-4-Methoxyphenyl]-2,3,4,9-tetrahydro-1H-Pyrido[3,4-b]indole-3-carboxylic Acid;(1R,3S)-1-[3-[[4-(2-Fluorophenyl)piperazin-1-yl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylic acid;1H-Pyrido[3,4-b]indole-3-carboxylic acid, 1-[3-[[4-(2-fluorophenyl)-1-piperazinyl]methyl]-4-methoxyphenyl]-2,3,4,9-tetrahydro-, (1R,3S)-

CAS号:

1354235-96-3

分子式:

C30H31FN4O3

分子量:

514.59

EINECS号:

相关类别:

化工原料;Aromatics, Heterocycles, Indole Derivatives, Inhibitors, Fluorescent Labels Indicators, Pharmaceuticals, Intermediates Fine Chemicals;Aromatics;Fluorescent Labels Indicators;Heterocycles;Indole Derivatives;Inhibitors;Intermediates Fine Chemicals;Pharmaceuticals

Mol文件:

1354235-96-3.mol

生物活性

trans-Ned 19 是一种 NAADP 拮抗剂和 TPC 阻断剂，抑制人脐静脉内皮细胞 (HUVEC) 中的钙信号 (calcium signal) 和响应低组胺浓度的大鼠主动脉松弛。

靶点

Ca 2+

Ca 2+