H-SIINFEKL-OH:SER-ILE-ILE-ASN-PHE-GLU-LYS-LEU

中文名称:

H-SIINFEKL-OH:SER-ILE-ILE-ASN-PHE-GLU-LYS-LEU

中文同义词:

OVA PEPTIDE (257-264)肽;鸡卵白蛋白 (257-264);L-丝氨酰-L-异亮氨酰-L-异亮氨酰-L—天冬酰胺酰-L-苯丙氨酰基-L-A-谷氨酰-L-赖氨酰-L-亮氨酸 三氟乙酸乙酯

英文名称:

H-SER-ILE-ILE-ASN-PHE-GLU-LYS-LEU-OH

英文同义词:

SER-ILE-ILE-ASN-PHE-GLU-LYS-LEU;SIINFEKL;OVALBUMIN(257-264) ANTIGEN PEPTIDE;OVALBUMIN (257-264) (CHICKEN);OVA (257-264);OVA (257-264) (CHICKEN);OVALBUMIN FRAGMENT - CHICKEN (257-264);OVA PEPTIDE (257-264)

CAS号:

138831-86-4

分子式:

C45H74N10O13

分子量:

963.13

EINECS号:

相关类别:

多肽;生化试剂-蛋白质;Peptide

Mol文件:

138831-86-4.mol

沸点 

1393.4±65.0 °C(Predicted)

密度 

1.244±0.06 g/cm3(Predicted)

储存条件 

-15°C

溶解度 

H2O: >1mg/mL

形态

lyophilized powder

酸度系数(pKa)

3.37±0.10(Predicted)

颜色

white to off-white

生物活性

OVA Peptide(257-264) 是 OVA 的 I 类 (Kb)-限制性肽表位，OVA 是由 I 类 MHC 分子 H-2Kb 呈递的来自卵清蛋白的八聚体肽。

体外研究

TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide(257-264) epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide(257-264) epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide(257-264) contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide(257-264) contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads.

WGK Germany 

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