7-Prenyloxyaromadendrin

中文名称:

7-Prenyloxyaromadendrin

中文同义词:

英文名称:

7-Prenyloxyaromadendrin

英文同义词:

7-Prenyloxyaromadendrin;4H-1-Benzopyran-4-one, 2,3-dihydro-3,5-dihydroxy-2-(4-hydroxyphenyl)-7-[(3-methyl-2-buten-1-yl)oxy]-, (2R,3R)-

CAS号:

78876-50-3

分子式:

C20H20O6

分子量:

356.37

EINECS号:

相关类别:

黄酮

Mol文件:

78876-50-3.mol

沸点 

624.3±55.0 °C(Predicted)

密度 

1.343±0.06 g/cm3(Predicted)

酸度系数(pKa)

7.27±0.60(Predicted)

生物活性

7-Prenyloxyaromadendrin 是一种来自 Pterocaulon alopecuroides 的类黄酮，具有抗肿瘤活性。7-Penyloxyaromadendrin 在肿瘤细胞系中显示出良好的抗增殖活性。

体外研究

7-Prenyloxyaromadendrin (compound 5) shows antiproliferative activity with GI 50 values in the range 16-20 μM in A549, HBL-100, HeLa, SW1573, T-47D cells. 7-Prenyloxyaromadendrin (compound 5) is inactive on B. subtilis and B. cereus (there is no zone of inhibition at the concentration of 50 μg/disk).