4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇

中文名称:

4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇

中文同义词:

O-去吗啉丙基吉非替尼;3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇;4-(3-氯-4-氟苯胺)-7-甲氧基-喹唑啉-6;吉非水解物;吉非水解物 4-(3-氯-4-氟苯氨基)-7-甲氧基喹唑啉-6-醇;4-(3-氯-4-氟苯胺)-6-羟基-7-甲氧基喹唑啉;4-(3-氯-4-氟苯胺基)-6-羟基-7-甲氧基喹唑啉;4-[(3-氯-4-氟苯基)氨基]-7-甲氧基-6-喹唑啉醇

英文名称:

4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol

英文同义词:

FAAH-IN-2;4-(3-Chloro-4-fluorophenylamino)-6-hydroxy-7-methoxyquinazoline;4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol;O-Desmorpholinopropyl Gefitinib;4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol;Gefitinib interMediate VII;4-(3-Chlor-4-fluorophenylamino)-7-methoxyquinazolin-6-ol;Gefitinib Intermediate 1

CAS号:

184475-71-6

分子式:

C15H11ClFN3O2

分子量:

319.72

EINECS号:

1806241-263-5

相关类别:

医药中间体;吉非替尼;抗肿瘤;中间体;陕西林奈主打产品;Gefitinib;Various Metabolites and Impurities;Intermediates Fine Chemicals;Metabolites Impurities;Pharmaceuticals

Mol文件:

184475-71-6.mol

熔点 

>260°C (dec.)

沸点 

478.8±45.0 °C(Predicted)

密度 

1.489±0.06 g/cm3(Predicted)

储存条件 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

酸度系数(pKa)

8.18±0.40(Predicted)

生物活性

FAAH-IN-2 (O-Desmorpholinopropyl Gefitinib) 是摘自专利WO/2008/100977A2中的 FAAH 抑制剂。

用途 

吉非替尼中间体