6-全脱氧-6-全溴代-Γ-环糊精

中文名称:

6-全脱氧-6-全溴代-Γ-环糊精

中文同义词:

八-(6-溴-6-脱氧)-伽马-环糊精;八-(6-溴-6-脱氧)-GAMMA-环糊精;八-(6-溴-6-脱氧)-GAMMA-环糊精 舒更葡糖钠中间体;舒更葡糖钠杂质38;舒更葡糖杂质3;八(6-溴-6-去氧)伽马环糊精;6-全脱氧-6-全溴代-Γ-环糊精;八(6-溴-6-去氧)-Γ-环糊精

英文名称:

OCTAKIS-6-BROMO-6-DEOXY-GAMMA-CYCLODEXTRIN

英文同义词:

Octakis(6-deoxy-6-bromo)-gamma-cyclodextrin;6-Bromo-6-deoxy-gamma-cyclodextrin;Octakis(6-bromo-6-dexoy)-gamma-cyclodextrin;octakis(6-bromo-6-deoxy)-γ-cyclodextrin;Sugammadex sodium Impurity 38;γ-Cyclodextrin,6A,6B,6C,6D,6E,6F,6G,6H-octabromo-6A,6B,6C,6D,6E,6F,6G,6H-octadeoxy;Sugammadex Impurity 1

CAS号:

53784-84-2

分子式:

C48H72Br8O32

分子量:

1800.3

EINECS号:

611-044-0

相关类别:

原料药中间体 舒更葡糖钠中间体;杂质对照品;对照品-杂质对照品

Mol文件:

53784-84-2.mol

熔点 

213-217°C

密度 

1.948±0.06 g/cm3(Predicted)

溶解度 

Soluble in DMF, DMSO. Insoluble in water, methanol, chloroform.

形态

Solid powder

酸度系数(pKa)

11.56±0.70(Predicted)

颜色

Off-white

生物活性

Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin 是一种在伯侧全溴化的γ-环糊精，也是一种环糊精改性中常用的中间体。

体外研究

Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin is stacked head-to-head along the a-axis forming columns. Octakis-(6-bromo-6-deoxy)-γ-cyclodextrin has a feature that alternates hydrophobic and hydrophilic layers are formed in the crystal.