(ALPHAS)-1,4-二氢-ALPHA-异丙基-N-[4-甲基-5-(5-甲基-1,3,4-恶二唑-2-基)-2-噻

中文名称:

(ALPHAS)-1,4-二氢-ALPHA-异丙基-N-[4-甲基-5-(5-甲基-1,3,4-恶二唑-2-基)-2-噻唑基]-2,4-二氧代-3(2H)-喹唑啉乙酰胺

中文同义词:

(ALPHAS)-1,4-二氢-ALPHA-异丙基-N-[4-甲基-5-(5-甲基-1,3,4-恶二唑-2-基)-2-噻唑基]-2,4-二氧代-3(2H)-喹唑啉乙酰胺;KIF15驱动蛋白抑制剂(KIF15-IN-2)

英文名称:

Kif15-IN-2

英文同义词:

Kif15-IN-2;(alphaS)-1,4-Dihydro-alpha-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-3(2H)-quinazolineacetamide;Kif15 inhibitor 2;3(2H)-Quinazolineacetamide, 1,4-dihydro-α-(1-methylethyl)-N-[4-methyl-5-(5-methyl-1,3,4-oxadiazol-2-yl)-2-thiazolyl]-2,4-dioxo-, (αS)-

CAS号:

672926-33-9

分子式:

C20H20N6O4S

分子量:

440.48

EINECS号:

相关类别:

细胞生物学试剂

Mol文件:

672926-33-9.mol

密度 

1.409±0.06 g/cm3(Predicted)

酸度系数(pKa)

7.58±0.50(Predicted)

生物活性

Kif15-IN-2 是一种驱动蛋白 Kif15 的抑制剂，主要用于细胞增殖性疾病的研究。

靶点

KIF15

KIF15

体外研究

Kif15-IN-2 (Compound 14) is an inhibitor of the mitotic kinesin Hs Kif15, with the potential activities against cellular proliferative diseases such as cancer, hyperplasias, restenosis, cardiac hypertrophy, immune disorders and inflammation.