GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL

中文名称:

GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL

中文同义词:

MELAN-A, MART 1 (26-35),EAAGIGILTV

英文名称:

H-GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL-OH

英文同义词:

H-GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL-OH;GLU-ALA-ALA-GLY-ILE-GLY-ILE-LEU-THR-VAL;EAAGIGILTV;ANTIGEN SK29-AA (26-35) (HUMAN);ANTIGEN LB39-AA (26-35) (HUMAN);MART 1 (26-35);MART-1 (26-35) (HUMAN);MELANOMA ANTIGEN RECOGNIZED BY T-CELLS 1 (26-35) (HUMAN)

CAS号:

156251-01-3

分子式:

C42H74N10O14

分子量:

943.1

EINECS号:

相关类别:

多肽;peptide

Mol文件:

156251-01-3.mol

沸点 

1358.4±65.0 °C(Predicted)

密度 

1.223±0.06 g/cm3(Predicted)

储存条件 

-20°C

酸度系数(pKa)

3.32±0.10(Predicted)

生物活性

MART-1 (26-35) (human) 是 MART-1 蛋白 26 至 35 氨基酸片段。

体外研究

MART-1 (Melan-A) gene is 18 kb long and comprises five exons. It is expressed in most melanoma tumor samples, and among normal cells, only in melanocytes. In cancer immunotherapy, epitopes and variants derived from the MART-1/Melan-A protein are widely used as clinical vaccines. The epitopes spanning amino acid residues 26–35 and 27–35 from the MART-1/Melan-A protein, highly expressed in melanoma cells, provide a prime example of T cell recognition of multiple peptides and the use of peptide variants designed to elicit altered immunological responses.