GLY-TYR-PRO-GLY-LYS-PHE-NH2

中文名称:

GLY-TYR-PRO-GLY-LYS-PHE-NH2

中文同义词:

小鼠PAR-4 (1-6) AMIDE肽;甘氨酰-L-酪氨酰-L-脯氨酰甘氨酰-L-赖氨酰-L-苯丙氨酰胺;蛋白酶活化的受体-4

英文名称:

H-GLY-TYR-PRO-GLY-LYS-PHE-NH2

英文同义词:

THROMBIN RECEPTOR-LIKE 3 (1-6) AMIDE (MOUSE);PAR-4 (1-6) AMIDE (MOUSE);PAR-4 AGONIST AMIDE;PROTEINASE ACTIVATED RECEPTOR 4 (1-6) AMIDE (MOUSE);PROTEASE-ACTIVATED RECEPTOR-4 AGONIST AMIDE;PROTEASE ACTIVATED RECEPTOR 4 (PAR 4) (60-65) AMIDE [MUS MUSCULUS];COAGULATION FACTOR II RECEPTOR-LIKE 3 (1-6) AMIDE (MOUSE);H2N-GYPGKF-AMIDE

CAS号:

245443-52-1

分子式:

C33H46N8O7

分子量:

666.77

EINECS号:

相关类别:

多肽;peptide

Mol文件:

245443-52-1.mol

沸点 

1150.7±65.0 °C(Predicted)

密度 

1.300±0.06 g/cm3(Predicted)

酸度系数(pKa)

9.84±0.15(Predicted)

生物活性

Protease-Activated Receptor-4 是转化生长因子受体 4 的激动剂。

体外研究

GYPGKF-NH2 significantly reduces the agonistic potency of AYPGKF-NH2 by 25-fold. GYPGKF-NH2 (500 μM) does not cause contraction or relaxation of the guinea pig IAS strips.