(2,3-二油氧基丙基)三甲基氯化铵

中文名称:

(2,3-二油氧基丙基)三甲基氯化铵

中文同义词:

1,2-三乙醇胺-3-三甲基丙烷;(2,3-二油氧基丙基)三甲基氯化铵;阳离子脂质材料DOTMA;MRNA脂质体磷脂辅料DOTMA;DOTAP(2,3-二油酰基-丙基)-三甲基铵-氯盐;(2,3-二油酰基-丙基)三甲基氯化铵;(2,3-二油酰基-丙基)-三甲胺;1,2-二油酰-3-三甲基丙基氯化铵(DOTAP)

英文名称:

N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

英文同义词:

1,2-DIOLEOYL-3-TRIMETHYLAMMONIUM-PROPANE, CHLORIDE;DOTMA;DOTAP CHLORIDE SALT;DOTAP;dotap chloride;N-[1-(2,3-DIOLEYLOXY)PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE;N-[1-(2,3-DIOLEOYLOXY)PROPYL]-N,N,N-TRIMETHYL-AMMONIUM CHLORIDE SALT;N-[1-(2,3-DIOLEOYLOXY) PROPYL]-N,N,N-TRIMETHYLAMMONIUM CHLORIDE

CAS号:

132172-61-3

分子式:

C42H80ClNO4

分子量:

698.54

EINECS号:

相关类别:

合成磷脂;高纯度合成磷脂;Fatty Acid Derivatives Lipids;Glycerols;Mixed Fatty Acids

Mol文件:

132172-61-3.mol

熔点 

35-38°C

储存条件 

-20°C

形态

lyophilized powder

稳定性

Store in Freezer, Hygroscopic

生物活性

DOTAP chloride (1,2-Dioleoyl-3-trimethylammonium-propane chloride) 是一种有效的阳离子脂质，广泛用作 liposomal transfection 试剂。DOTAP 也是动物细胞中先天免疫系统的强激活剂，可作为研究植物免疫性的引发剂的潜在候补。

靶点

IC50: Cationic Lipid

体外研究

liposomes are reorganized by associating with DNA. The transfection efficiency of DOTAP liposomes is mainly influenced by lipid composition and cell type, but not by size or zeta potential.

WGK Germany 

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