中文名称:

GLY-ARG-GLY-ASP-SER

中文同义词:

甘氨酰精氨酰甘氨酰天门冬氨酰丝氨酸

英文名称:

GLY-ARG-GLY-ASP-SER

英文同义词:

GRGDS;GRGDS 1/2ACOH 2H2O;GRGDS, FIBRONECTIN ATTACHMENT PEPTIDE;GLY-ARG-GLY-ASP-SER;GLY-ARG-GLY-ASP-SER 1/2ACOH 2H2O;H-GLY-ARG-GLY-ASP-SER-OH;L-Serine, N-(N-(N-(N2-glycyl-L-arginyl)glycyl)-L-alpha-aspartyl)-;glycyl-arginyl-glycyl-aspartyl-serine

CAS号:

96426-21-0

分子式:

C17H30N8O9

分子量:

490.47

EINECS号:

相关类别:

多肽;Cell Signaling Enzymes;ECM Related Proteins and PeptidesCytoskeleton and Extracellular Matrix;Extracellular Matrix;Extracellular Matrix Peptides (ECM);Extracellular Matrix Peptides and ProteinsPeptides for Cell Biology;Fibronectin Fragments and Analogs;Matrix Metalloproteinases Products;peptide

Mol文件:

96426-21-0.mol

密度 

1.66±0.1 g/cm3(Predicted)

储存条件 

-20°C

形态

White to off-white lyophilized solid

酸度系数(pKa)

2.85±0.10(Predicted)

生物活性

Gly-Arg-Gly-Asp-Ser 是一种五肽，构成了糖蛋白，骨桥蛋白与细胞的结合域。

靶点

IC50: 5 μM (αvβ3), 6.5 μM (αvβ5)

体外研究

Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3, with IC 50 of 5 μM. Gly-Arg-Gly-Asp-Ser-immobilized TiO2 nanotubes enhance osteoblast-like cell (MG-63) adhesion, and significantly increased cell spreading and proliferation.

WGK Germany 

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