中文名称:

卡前列素氨基丁三醇

中文同义词:

卡前列腺氨丁三醇;卡前列素氨基丁三醇;(Z)-7-[(3R,5S)-3,5-二羟基-2-[(E,3S)-3-羟基-3-甲基辛-1-烯基]环戊基]庚-5-烯酸氨基丁三醇;卡前列素丁三醇;卡前列素(卡前列素丁三醇);卡前列素氨丁三醇;卡前列素氨基丁三醇58551-69-2,工厂零售58551-69-2;卡前列腺素杂质

英文名称:

Carboprost tromethamine

英文同义词:

7-[3,5-dihydroxy-2-(3-hydroxy-3-methyloct-1-enyl)cyclopentyl]-5-heptenoic acid;Carboprost tromethamine (W.S);(Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3S)-3-hydroxy-3-methyloct-1-enyl]cyclopentyl]hept-5-enoic acid;(5Z,9α,11α,15E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid tris(hydroxymethyl)aminomethane salt;Carboprost TroMethaniMine;(5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15- methylprosta-5,13-dien-1-oic acid with 2-amino-2-(hydroxymethyl)-1,3-propanediol (1:1);Carboprost Tromethamine (30 mg);CARBOPROST TROMETHAMINE (MEIS SL NO :1115 GROUP-B-29)

CAS号:

58551-69-2

分子式:

C21H36O5.C4H11NO3

分子量:

489.64

EINECS号:

相关类别:

前列腺素类;医药原料药;前列素类;杂质对照品;原料药;Prostaglandins

Mol文件:

58551-69-2.mol

溶解度 

Soluble in water.

形态

neat

InChIKey

UMMADZJLZAPZAW-XOWPVRJPSA-N

生物活性

Carboprost tromethamine 是前列腺素 F2α (prostaglandin F2α) 的 15 甲基类似物。Carboprost tromethamine 能有效促进子宫规律性收缩，显著减少产后出血量。

体内研究

Carboprost tromethamine has a significant effect on the prevention of postpartum hemorrhage in cesarean section, and has a significant effect on improving the state of hypercoagulable blood and maintaining the stable hemodynamic state. Carboprost tromethamine has been accounted for to be 84-96% successful in the treatment of persistent hemorrhage because of uterine atony.

海关编码 

2937500000