D-蛋氨酸
中文名称:
D-蛋氨酸
中文同义词:
D-2-氨基-4-甲硫基丁酸;D-蛋氨酸;D-甲硫氨酸(D-蛋氨酸);D-甲硫氨酸/D-蛋氨酸/D-2-氨基-4-甲硫基丁酸/D-甲硫基丁氨酸;D-METHIONINE D-蛋氨酸;D-甲硫氨酸,D-2-氨基-4-甲硫基丁酸;D-蛋氨酸,99%;D-蛋氨酸/D-甲硫氨酸
英文名称:
D-Methionine
英文同义词:
D-2-AMINO-4-[METHYLTHIO]BUTANOIC ACID;d-2-amino-4-(methylthio)butyric acid;H-D-MET-OH;D-LOBAMINE;D-METHIONINE;D-BANTHIONINE;(R)-2-AMINO-4-(METHYLMERCAPTO)BUTYRIC ACID;(2R)-2-Amino-4-methylsulfanylbutanoic acid
CAS号:
348-67-4
分子式:
C5H11NO2S
分子量:
149.21
EINECS号:
206-483-6
相关类别:
D系列氨基酸;氨基酸及其衍生物;生化试剂;精细化学品;氨基酸;其他生化试剂;保护氨基酸;氨基酸和衍生物;氨基酸类;保护氨基酸及多肽类产品;化学生物学;标准品;非天然氨基酸;医药原料;氨基酸 Amino Acid;天然氨基酸极其衍生物;氨基酸衍生物;营养增补剂;化学试剂;中药对照品;对照品;Amino ACIDS SERIES;Amino Acid Derivatives;PROTECTED AMINO ACID PEPTIDES;Methionine [Met, M];Amino Acids and Derivatives;Amino Acids and Derivatives;Amino Acids;生化试剂-氨基酸类;原料药API;原料;生化试剂-氨基酸;D-氨基酸;有机化工原料;有机中间体
Mol文件:
348-67-4.mol
熔点
273-275 °C
比旋光度
-24 º (c=8, 6N HCl)
沸点
306.9±37.0 °C(Predicted)
密度
1.113 (estimate)
折射率
1.5216 (estimate)
储存条件
Sealed in dry,Room Temperature
溶解度
53 g/L (20°C)
酸度系数(pKa)
2.23±0.10(Predicted)
形态
Powder
颜色
White to off-white
水溶解性
53 g/L (20 ºC)
Merck
14,5975
BRN
1722293
稳定性
Stable. Incompatible with strong oxidizing agents.
CAS 数据库
348-67-4(CAS DataBase Reference)
NIST化学物质信息
D-(l)-Methionine(348-67-4)
EPA化学物质信息
D-Methionine (348-67-4)
生物活性
Methionine (MRX-1024; D-Methionine) 是一种有效的化学保护剂，它还可以通过激活 GABAA 受体来抑制神经元活性。
靶点
GABA A receptor
体外研究
The incubation of human plasma with Methionine (D-methionine) and CP leads to the formation of a Pt-D-methionine complex independent of the order of addition. In plasma, an early CP hydrolysis product reacts with Methionine to form a 1:1 complex that is followed by the formation of a 2:1 compound at a later time point. The formation of these Pt-D-methionine species plays an important role in the processes by which Methionine protects mammalian organisms against CP-induced toxicities.
体内研究
When Methionine (D-methionine) is administered along with cisplatin the cell density is 0.8±0.070 (SEM), significantly larger than in rats treated with only cisplatin (P<0.01) while not significantly different from controls or from animals treated only with D-methionine (P>0.05). When Methionine is administered alone the average cell density is 0.95±0.099 (SEM) and not significantly different from controls (P>0.05).
化学性质
D-蛋氨酸为白色结晶。溶于水、稀酸及碱，极微溶于醇，不溶于醚。
用途
用作生化试剂。
用途
用于生化研究和营养增补剂
危险品标志
Xi
危险类别码
33-36/37/38
安全说明
22-24/25-36-26
WGK Germany
3
RTECS号
PD0455000
TSCA
Yes
海关编码
29304090
