中文名称:

6-羧基荧光素

中文同义词:

6-羧基荧光素;6-羧基荧光素 25G;6-FAM [6-羧基荧光素];6-羧基荧光素(单一化合物);6-羧基荧光素,6-FAM

英文名称:

6-Carboxyfluorescein

英文同义词:

3-Oxo-3,6-dihydroxy-1,3-dihydrospiro[isobenzofuran-1,9-[9H]xanthene]-6-carboxylic acid;Carboxyfluorescein;3,6-dihydroxy-1-keto-spiro[isobenzofuran-3,9-xanthene]-5-carboxylic acid;3,6-dihydroxy-1-oxo-spiro[2-benzofuran-3,9-xanthene]-5-carboxylic acid;3,6-dihydroxy-1-oxospiro[2-benzofuran-3,9-xanthene]-5-carboxylic acid;6-Carboxyfluorescein,6-FAM, FLUOS;6-Carboxyfluorescein Hydrate;6-FAM, 6-CF

CAS号:

3301-79-9

分子式:

C21H12O7

分子量:

376.32

EINECS号:

636-503-2

相关类别:

荧光探针，标记，颗粒和染色;有机原料;亚磷酰胺(phosphoramidite);荧光素类，荧光染料;荧光标记染料;生化试剂;羧酸类衍生物;Electronic Chemicals;Fluorescent Labels and Indicators;Fluorescent Labels Indicators;marker;Fluorescent;Xanthene;有机化工原料

Mol文件:

3301-79-9.mol

熔点 

>300 °C(lit.)

沸点 

736.4±60.0 °C(Predicted)

密度 

1.73±0.1 g/cm3(Predicted)

储存条件 

Sealed in dry,2-8°C

溶解度 

DMSO: soluble

酸度系数(pKa)

3.3, 4.6, 6.4, 7.0(at 25℃)

形态

Solid

颜色

Yellow to orange

酸碱指示剂变色ph值范围

Weak green uorescence (6.0) to strong green uourescence (7.2)

最大波长(λmax)

492nm

BRN 

54341

生物领域应用

Diagnosing bladder cancer; evaluating corneal endothelial barrier function; as a substrate for measuring protein kinase activity, methyltransferase activity, phospholipase activity, rhodanese activity,sulfotransferase activity;use in ophthalmology

主要应用

Diagnosis of hematologic cancer, nongastric diseases, detection of genetically modified wheat, chromosomes, gene expression, nucleic acid, hepatitis A virus, avian influenza virus subtype H5 and H5N1, SARS virus, herpex simplex virus

CAS 数据库

3301-79-9(CAS DataBase Reference)

EPA化学物质信息

Spiro[isobenzofuran-1(3H),9-[9H]xanthene]-6-carboxylic acid, 3,6-dihydroxy-3-oxo- (3301-79-9)

生物活性

6-FAM (6-Carboxyfluorescein) 是羧基荧光素的一个同分异构体，主要用于核酸的测序和标记。

危险品标志 

Xi

危险类别码 

36/37/38

安全说明 

26-36/37

WGK Germany 

3

F 

10-21

海关编码 

3204 90 00