中文名称:

7-木糖甙-10-脱乙酰基紫杉醇

中文同义词:

7-木糖甙-10-脱乙酰基紫杉醇;7-木糖苷-10-脱乙酰基紫杉醇;7-木糖-10-去乙酰紫杉醇;-木糖苷-10-脱乙酰基紫杉醇;7-木糖苷-10-脱乙酰基;7-木糖基-10-去乙酰基紫杉醇;10-去乙酰-7-木糖紫杉醇;7-木糖紫杉醇(7木糖10去乙酰基紫杉醇)

英文名称:

7-Xylosyl-10-deacetyltaxol

英文同义词:

7-XYLOSYL-10-DEACETYLTAXOL;10-Deacetylpaclitaxel 7-Xyloside;DEACETYL-7-XYLOTAXOL, 10-(P);10-Deacetyl-7-xylosyl Paclitaxel (62%);7-XYLOXYL-10-DEACETYL TAXOL;10-Deacetyltaxol 7-xyloside;b-(Benzoylamino)-a-hydroxy-benzenepropanoic acid [2aR-[2aa,4b,4ab,6b,9a(aR*,bS*),11a,12a,12aa,12ba]]-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-4-(b-D-xylopyranosyloxy)-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester;Benzenepropanoic acid, b-(benzoylaMino)-a-hydroxy-,(2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-6,11-dihydroxy-4a,8,13,13-tetraMethyl-5-oxo-4-(b-D-xylopyranosyloxy)-7,11-Methano-1H-cyclo

CAS号:

90332-63-1

分子式:

C50H57NO17

分子量:

943.98

EINECS号:

相关类别:

标准品;植物提取物;原料;对照品-中药对照品;二萜;标准品 -中药标准品;Aromatics;Chiral Reagents;Heterocycles;Intermediates Fine Chemicals;Metabolites Impurities;Pharmaceuticals

Mol文件:

90332-63-1.mol

沸点 

1068.4±65.0 °C(Predicted)

密度 

1.46±0.1 g/cm3(Predicted)

酸度系数(pKa)

11.26±0.70(Predicted)

生物活性

10-Deacetyl-7-xylosyl paclitaxel 是 Paclitaxel (一种 microtubule 稳定剂，增强 tubulin 聚合) 的衍生物，相比 Paclitaxel，具有更好的药学活性。

靶点

Traditional Cytotoxic Agents

Traditional Cytotoxic Agents

化学性质 

白色结晶粉末，可溶于甲醇、乙醇、DMSO等有机溶剂，来源于红豆杉。

用途 

抗癌抗肿瘤。