中文名称:

藤黄菌素

中文同义词:

LUTEOLIN-5-O-GLUCOSIDE 木犀草素-5-O-葡萄糖苷;木犀草素 5-葡萄糖苷;木犀草素-5-O-葡萄糖苷;木犀草素-5-O-葡萄糖苷对照品

英文名称:

Luteolin-5-O-β-D-glucopyranoside

英文同义词:

5-(β-D-Glucopyranosyloxy)-7-hydroxy-2-(3,4-dihydroxyphenyl)-4H-1-benzopyran-4-one;5-[(β-D-Glucopyranosyl)oxy]-3,4,7-trihydroxyflavone;Luteolin 5-glucoside;Luteolin-5-O-β-D-glucopyranoside;2-(3,4-Dihydroxyphenyl)-5-(beta-D-glucopyranosyloxy)-7-hydroxy-4H-1-benzopyran-4-one;Luteolin 5-beta-D-glucopyranoside;Luteolin 5-O-beta-D-glucopyranoside;Luteolin-5-O-beta-D-glucoside

CAS号:

20344-46-1

分子式:

C21H20O11

分子量:

448.38

EINECS号:

相关类别:

植物提取物;对照品;标准品;中药对照品;分析试剂标准品;中药标准品;对照品-中药对照品;黄酮;标准品 -中药标准品

Mol文件:

20344-46-1.mol

熔点 

260-263℃

沸点 

864.2±65.0 °C(Predicted)

密度 

1.713

储存条件 

Sealed in dry,2-8°C

酸度系数(pKa)

6.42±0.40(Predicted)

生物活性

Luteolin 5-O-glucoside 来自 Cirsium maackii，具有抗炎活性。Luteolin 5-O-glucoside 抑制 LPS 诱导的 NO 生成和 t-BHP 诱导的 ROS 生成。Luteolin 5-O-glucoside 作用于巨噬细胞，还抑制 iNOS 和 COX-2 表达。

体外研究

Luteolin 5-O-glucoside, at a non-toxic concentration, inhibits LPS-induced NO production and t-BHP-induced ROS generation in a dose-dependent manner in RAW 264.7 cells. Luteolin 5-O-glucoside also suppresses the expression of iNOS and COX-2 in LPS-stimulated macrophages.