中文名称:

EPSILON-VINIFERIN

中文同义词:

EPSILON-白藜芦醇脱氢二聚体;反式-E-葡萄素;Ε-葡萄素标准品

英文名称:

epsilon-viniferin

英文同义词:

epsilon-viniferin;(-)-5-[[(2R)-2,3-Dihydro-6-hydroxy-2β-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)vinyl]benzofuran]-3α-yl]-1,3-benzenediol;(2R)-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-(4-hydroxy-trans-styryl)-2,3-dihydrobenzofuran-6-ol;(2R)-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-[(E)-4-hydroxystyryl]-2,3-dihydrobenzofuran-6-ol;[2R,(-)]-2β-(4-Hydroxyphenyl)-3α-(3,5-dihydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydrobenzofuran-6-ol;5-[(2R,3R)-6-hydroxy-2-(4-hydroxyphenyl)-4-[(E)-2-(4-hydroxyphenyl)ethenyl]-2,3-dihydrobenzofuran-3-yl]benzene-1,3-diol;e-viniferin;(-)-trans-epsilon-viniferin

CAS号:

62218-08-0

分子式:

C28H22O6

分子量:

454.47

EINECS号:

相关类别:

中药对照品;标准品;植物提取物;其它酚类

Mol文件:

62218-08-0.mol

熔点 

approximate 157℃ (dec.)

生物活性

ε-Viniferin 是从Vitis vinifera 提取得到的，Resveratrol 的二聚体，可有效抑制 CYP 家族，Ki 值在0.5-20 μM 之间。ε-Viniferin 具有强大的抗氧化活性。

靶点

CYP2B6 3 μM (Ki, (BROD)) CYP1A2 5 μM (Ki, (EROD)) CYP3A4 10 μM (Ki, (TST)) CYP4A 15 μM (IC 50 , (LwOH)) CYP2E1 25 μM (IC 50 , (CHZ)) CYP2A6 60 μM (Ki, (COH))

CYP2B6 3 μM (Ki, (BROD))

CYP1A2 5 μM (Ki, (EROD))