异香兰素

中文名称:

异香兰素

中文同义词:

3-羟基-4-甲氧基苯甲醛;异香草醛,98%;异香草醛(3-羟基-4-甲氧基苯甲醛);3-羟基茴香醛;异香兰素( 异香草醛,异香兰醛,3-羟基-4-甲氧基苯甲醛,3-羟基大茴香醛,原儿茶醛-4-甲醚,异香荚兰素);ISOVANILLIN 异香兰素;3-羟基-4-甲氧基苯;3-羟基-4-甲氧基苯甲醛 25G

英文名称:

Isovanillin

英文同义词:

ISOVANILIN;ISOVANILLIN;3-HYDROXY-4-ANISALDEHYDE;3-HYDROXY-4-METHOXYBENZALDEHYDE;3-HYDROXYANISALDEHYDE;3-HYDROXY-P-ANISALDEHYDE;AKOS B022473;AKOS BBS-00003278

CAS号:

621-59-0

分子式:

C8H8O3

分子量:

152.15

EINECS号:

210-694-9

相关类别:

对照品;标准品;通用试剂;其他生化试剂;醛;芳香醛;羰基化合物;中药对照品;有机砌块;植物提取物;医药原料;食品添加剂;香精香料;生化试剂;中间体;化工原料;无机盐;对照品-中药对照品;FINE Chemical INTERMEDIATES;Aromatic Aldehydes Derivatives (substituted);BenzaldehydeDerivative;Benzaldehyde;Aromatics;Matrix Substances for MALDI-MS;Aldehydes;Analytical Reagents;Analytical/Chromatography;Building Blocks;C8;Carbonyl Compounds;Chemical Synthesis;Mass Spectrometry;Mass Spectrometry (MS);Matrices for MALDI Analysis;其他原料;标准品 -中药标准品;有机化学;标准品，对照品;医药、农药及染料中间体;有机化工原料;合成香料;化工原料;Organic Building Blocks;Proteomics;Spectroscopy;Piperidines ,Piperazines ,Homopiperidines;API

Mol文件:

621-59-0.mol

熔点 

113-116 °C

沸点 

179 °C15 mm Hg(lit.)

密度 

1.20

折射率 

1.4945 (estimate)

闪点 

179°C/15mm

储存条件 

-20°C Freezer, Under Inert Atmosphere

溶解度 

Soluble in acetone and methanol.

酸度系数(pKa)

pK1:8.889 (25°C)

形态

crystalline

颜色

faintly brown

敏感性 

Air Sensitive

BRN 

1073021

InChIKey

JVTZFYYHCGSXJV-UHFFFAOYSA-N

CAS 数据库

621-59-0(CAS DataBase Reference)

NIST化学物质信息

Benzaldehyde, 3-hydroxy-4-methoxy-(621-59-0)

EPA化学物质信息

Benzaldehyde, 3-hydroxy-4-methoxy- (621-59-0)

生物活性

Isovanillin (5-Formylguaiacol, 3-Hydroxy-p-anisaldehyde, 3-Hydroxy-4-methoxybenzaldehyde)是醛脱氢酶（aldehyde oxidase）的可逆性抑制剂。它被广泛用作药物中间体，应用于食物和饮料行业、化学合成香料和化学分析领域。

靶点

Target Value aldehyde oxidase ()

Target

Value

aldehyde oxidase ()

体外研究

Isovanillin is not a substrate for aldehyde oxidase and therefore it is metabolized to isovanillic acid predominantly by aldehyde dehydrogenase. Isovanillin is relaxant of ileum contractions induced by 5-HT (IC 50 =356±50μM) .

体内研究

Isovanillin (2 mg/kg 5 mg/kg) and iso-acetovanillon (2 mg/kg 5 mg/kg) both have antidiarrheal and anti-motility effect on gastrointestinal tract.

化学性质 

淡黄色结晶粉末。熔点113-115℃。

用途 

用于香料及医药中间体

危险品标志 

Xi

危险类别码 

36/37/38

安全说明 

26-36/37-36

WGK Germany 

3

RTECS号

CU6540000

Hazard Note 

Irritant

TSCA 

Yes

海关编码 

29124900