苯扎隆

中文名称:

苯扎隆

中文同义词:

2-乙基-3-对羟基苯甲酰基苯并呋喃;2-乙基-3-(4-羟基苯甲酰基)苯并呋喃;苯溴马隆杂质C;苯萨容;苯扎隆;苯溴马隆杂质C(EP);苯扎隆 EP标准品

英文名称:

Benzarone

英文同义词:

2-Ethyl-3-p-hydroxybenzoylbenzofuran;Benzarone;2-Ethylbenzofuran-3-yl 4-hydroxyphenyl ketone;Benzaron;L 2197;Venagil;(2-ethylbenzofuran-3-yl)-(4-hydroxyphenyl)methanone;NSC 82134

CAS号:

1477-19-6

分子式:

C17H14O3

分子量:

266.29

EINECS号:

216-026-2

相关类别:

医药原料药;杂环化合物;原料药;(benzarone);Heterocycles;Heterocyclic Compound

Mol文件:

1477-19-6.mol

熔点 

124.3°

沸点 

369.5°C (rough estimate)

密度 

1.1601 (rough estimate)

折射率 

1.5490 (estimate)

储存条件 

Sealed in dry,2-8°C

形态

neat

酸度系数(pKa)

7.68±0.15(Predicted)

EPA化学物质信息

Methanone, (2-ethyl-3-benzofuranyl)(4-hydroxyphenyl)- (1477-19-6)

用途 

Benzarone is an EYA (Eyes Absents), multifunctional protein involved in organogenesis, inhibitor which makes it a potent anticancer agent. EYA鈥檚 are over expressed in ovarian and breast cancers. As we ll it is involved in the synthesis of Human Uric Acid Transporter 1 inhibitors which may be used to treat kidney diseases.

类别

易燃液体

毒性分级

高毒

急性毒性

腹腔-小鼠 LD50: 200 毫克/公斤

可燃性危险特性

易燃; 燃烧产生刺激烟雾

储运特性

通风低温干燥; 与库房食品原料分开存放

灭火剂

干粉,泡沫,沙土,二氧化碳, 雾状水

毒性

LD50 ipr-mus: 200 mg/kg AIPTAK 154,94,65