番木瓜碱

中文名称:

番木瓜碱

中文同义词:

番木瓜鹼;番木瓜碱

英文名称:

carpaine

英文同义词:

carpaine;(1S,11R,13S,14S,24R,26S)-13,26-Dimethyl-2,15-dioxa-12,25-diazatricyclo[22.2.2.211,14]triacontane-3,16-dione;2,15-Dioxa-12,25-diazatricyclo[22.2.2.211,14]triacontane-3,16-dione,13,26-dimethyl-, (1S,11R,13S,14S,24R,26S)-

CAS号:

3463-92-1

分子式:

C28H50N2O4

分子量:

478.71

EINECS号:

222-414-2

相关类别:

标准品;中药对照品

Mol文件:

3463-92-1.mol

熔点 

119-120°

比旋光度 

D12 +24.7° (c = 1.07 in ethanol)

沸点 

577.37°C (rough estimate)

密度 

1.0566 (rough estimate)

折射率 

1.5800 (estimate)

酸度系数(pKa)

9?+-.0.60(Predicted)

生物活性

Carpaine 番木瓜碱是一种从 Carica papaya Linn 中分离出的具有抗血小板减少活性的生物碱，在维持血小板数目方面表现出强烈的活性，无急性毒性。Carpaine 具有抗疟疾活性以预防疟疾。

体内研究

Carpaine affects the myocardium directly, it reduces cardiac output, stroke volume, stroke work, and cardiac power in rat, which has been studied for its cardiovascular effects.