中文名称:
3-十八烷基-2-[3-(3-十八烷基-2(3H)-苯并恶唑-2-亚基)-1-丙烯-1-基]苯并恶唑高氯酸盐
中文同义词:
3-十八烷基-2-[3-(3-十八烷基-2(3H)-苯并恶唑-2-亚基)-1-丙烯-1-基]苯并恶唑高氯酸盐;细胞膜绿色荧光探针(DIO);DIO高氯酸盐;DIO细胞膜荧光探针绿色;DID 高氯酸盐;DIO(细胞膜绿色荧光探针);3,3`-双十八烷基氧碳花菁高氯酸盐;3,3-二-N-十八烷基氧代羰花青高氯酸盐
英文同义词:
3,3’-dioctadecyloxacarbocyanine;N,N-DIOCTADECYLOXACARBOCYANINE PERCHLORATE;NK 3045;DIOC18(3);DIO;D275;BENZOXAZOLIUM, 3-OCTADECYL-2-[3-(3-OCTADECYL-2(3H)-BENZOXAZOLYLIDENE)-1-PROPENYL]-, PERCHLORATE;BENZOXAZOLIUM, 3-OCTADECYL-2-[3-(3-OCTADECYL-2-BENZOXAZOLINYLIDENE)PROPENYL]-, PERCHLORATE
相关类别:
细胞生物学试剂;荧光探针，标记，颗粒和染色;荧光素染料;试剂;细胞分析;细胞相关;细胞组织染色;分子生物试剂-细胞相关
稳定性
Stability Stable, but light sensitive. Incompatible with strong oxidizing agents.
InChIKey
GFZPJHFJZGRWMQ-UHFFFAOYSA-M
生物活性
3,3′-Dioctadecyloxacarbocyanine perchlorate 是一种细胞膜绿色荧光探针。在进入细胞膜之前荧光非常弱，仅当进入到细胞膜后才可以被激发出很强的荧光。
体外研究
A fluorescent dialkyl carbocyanine dye (DiOC18(3)) is used to label muscle membranes, and the membranes accessible to the dye were observed by confocal laser scanning microscopy. A loss of cell membrane integrity results from contractile activity, enabling DiOC18(3) staining of internal membranes. The resulting staining pattern is striking and fibers with damaged cell membranes are easily distinguished from uninjured ones. 3,3′-Dioctadecyloxacarbocyanine perchlorate is a cationic oxacarbocyanine dye. The absorption and fluorescence spectra of 3,3-dioctadecyloxacarbocyanine, a cationic oxacarbocyanine dye have been studied in aqueous and nonaqueous media containing egg phosphatidylcholine (PC) as well as in different solvents of diverse nature. The results show the evidence of complex formation of the dye in the ground and in the excited states with PC. The excited state interaction of the dye with PC suggests the electron transfer from PC to dye and this is supported by photovoltage generation in a photoelectrochemical cell consisting of dye and PC in aqueous medium.
