D-γ-生育

中文名称:

D-γ-生育酚

中文同义词:

D-GAMMA-生育酚/D-GAMMA-维生素E;Α-生育酚;維生素E;維他命E;GAMMA-维生素E;D-GAMMA-生育酚;D-Γ-生育酚溶液,100PPM;[2R-[2R*(4R*,8R*)]]-3,4-二氢-2,7,8-三甲基-2-(4,8,12-三甲基十三烷基)-2H-1-苯并吡喃-6-醇

英文名称:

D-gamma-Tocopherol

英文同义词:

3,4-dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-,[2R-[2R*(4R*,8R*)]]-2H-1-Benzopyran-6-ol;3,4-dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-o;(R,R,R)-γ-Tocopherol;[2R[2R*(4R*,8R*)]]-3,4-dihydro-2,7,8-trimethyl-2-(4,8,12-trimethyltridecyl)-2H-benzopyran-6-ol;GAMMA-TOCOPHEROL, 25MG, NEAT;VITAMIN E(GAMMA)(REAGENT / STANDARD GRADE);(+)-GAMMA-TOCOPHEROL;D-GAMMA-TOCOPHEROL

CAS号:

54-28-4

分子式:

C28H48O2

分子量:

416.68

EINECS号:

200-201-5

相关类别:

营养学研究;维生素;标准品;对照品;中药对照品;通用试剂;Aromatics;Chiral Reagents;Heterocycles;Intermediates Fine Chemicals;Pharmaceuticals;其他生化试剂;生化试剂-维生素

Mol文件:

54-28-4.mol

比旋光度

30 º (C=2.0 IN ISOOCTANE 25 ºC)

沸点

200 °C (0.1 mmHg)

密度

0.9882 (rough estimate)

折射率

n20/D 1.505

闪点

9℃

储存条件

2-8°C

酸度系数(pKa)

11.05±0.40(Predicted)

形态

Viscous Liquid

颜色

Clear light brown

Merck

13,9573

BRN

93072

CAS 数据库

54-28-4(CAS DataBase Reference)

EPA化学物质信息

D-.gamma.-Tocopherol (54-28-4)

生育酚衍生物

生育酚主要有四种衍生物，按甲基位置分为α、β、γ和δ四种。与生育酚相关的化合物生育三烯酚在取代基不同时活性是一定的，但生育酚的活性会明显降低。下为二者结构简式：下表列出用以下官能团取代后生育三烯酚与生育酚的活性比：

生物活性

γ-Tocopherol (D-γ-Tocopherol) 是有效的环氧合酶 (cyclooxygenase) 抑制剂。γ-Tocopherol 是维生素 E 的天然形式，存在于许多植物种子中，例如玉米油和大豆。γ-Tocopherol 具有抗炎特性和抗癌活性。

靶点

Cyclooxygenase

体外研究

γ-Tocopherol (D-γ-Tocopherol) is well absorbed and accumulates to a significant degree in some human tissues; it is metabolized, however, largely to 2,7,8-trimethyl-2-(beta-carboxyethyl)-6-hydroxychroman (gamma-CEHC), which is mainly excreted in the urine. Plasma concentrations of γ-Tocopherol (D-γ-Tocopherol) are inversely associated with the incidence of cardiovascular disease and prostate cancer.

危险品标志

F,T

危险类别码

11-23/24/25-39/23/24/25

安全说明

24/25-45-36/37-16-7

危险品运输编号

UN1230 - class 3 - PG 2 - Methanol, solution

WGK Germany

8-10-23

海关编码

29362800