中文名称:

硫酸异帕米星

中文同义词:

硫酸异帕米星

英文名称:

Isepamicin sulfate

英文同义词:

(s)-y-1-oxopropyl)-2-deoxysulfate(salt);(2S)-3-amino-N-[(1R,2S,3S,4R,5S)-5-amino-4-[(2R,3R,4S,5S,6R)-6-(aminomethyl)-3,4,5-trihydroxy-oxan-2-yl]oxy-2-[(2R,3R,4R,5S)-3,5-dihydroxy-5-methyl-4-methylamino-oxan-2-yl]oxy-3-hydroxy-cyclohexyl]-2-hydroxy-propanamide sulfate;4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl]-N1-[(S)-3-amino-2-hydroxy-1-oxopropyl]-2-deoxy-D-streptamine/sulfuric acid;Elpacin;Isecin;Siosecin;IsepaMicine Sulphate;Isepamicine (Isepamycin

CAS号:

67814-76-0

分子式:

C22H45N5O16S

分子量:

667.68

EINECS号:

1592732-453-0

相关类别:

抗生素;小分子抑制剂，天然产物;医药原料药;Inhibitors;http://www.higherbio.com/a/gb2312/product/yuanliaoyao/2011/0711/67814-76-0.html;Antibacterial

Mol文件:

67814-76-0.mol

比旋光度 

D26 +110.9° (c = 1 in water as the disulfate hydrate)

储存条件 

Inert atmosphere,2-8°C

生物活性

Isepamicin Sulphate (Isepamicine, Isepamycin, sch21420) 是一种氨基糖苷类antibiotic，以细菌30S核糖体亚基为靶点抑制细菌蛋白质的合成。

毒性

LD50 in male, female mice, rats (mg/kg): 234, 236, 489, 476 i.v.; 3312, 3320, 3451, 3392 s.c.; >5000 orally both species (Morino)