中文名称:

醋酸缩宫素

中文同义词:

羟可待酮鉴别;羟可待酮鉴别 USP标准品;醋酸缩宫素

英文名称:

Oxytocin, monoacetate (salt)

英文同义词:

Oxytocin Identification (15 mg) (COLD SHIPMENT REQUIRED);Orasthin Acetate;Oxytocin Monoacetate;Perlacton Acetate;Pitocin Acetate;Synpitan Acetate;Syntocinon Acetate;Uteracon Acetate

CAS号:

6233-83-6

分子式:

C2H4O2

分子量:

60.05196

EINECS号:

228-347-5

相关类别:

原料药;药物多肽;Amino Acids Derivatives;Intermediates Fine Chemicals;Pharmaceuticals

Mol文件:

6233-83-6.mol

生物活性

Oxytocin acetate 是一种多效的下丘脑肽 (hypothalamic peptide)，有助于分娩、哺乳和亲社会行为。Oxytocin acetate 可以作为一种压力应对分子，具有抗炎、抗氧化剂和保护作用，特别是在面对逆境或创伤时。

体内研究

During the LMA task, rat core body temperature are modestly decreased. Oxytocin acetate (subcutaneous injection; 0.1 mg/kg-0.3 mg/kg; single dose) produces significantly greater hypothermia (at 0.3 mg/kg) than either saline or the two lower doses of oxytocin. Oxytocin at 0.3 mg/kg produces a significantly greater decrease in temperature than vehicle between 15-60 min post injection, whereas 0.1 mg/kg slightly decreases temperature at the 30 min time point only.Oxytocin acetate (0.1 mg/kg) engages in significantly more body sniffing and ano-genital sniffing compared with saline controls. It also increases the total time spent in social interaction (71.6±4.3 s), compared to those receiving vehicle (56.9±4.1 s). Animal Model: Fifty-six male Lister-hooded rats (150–200 g) Dosage: 0.1 mg/kg-0.3 mg/kg Administration: Subcutaneous injection; 0.1 mg/kg-0.3 mg/kg; single dose Result: Produced significantly greater hypothermia (at 0.3 mg/kg) than the saline group.

Animal Model:

Fifty-six male Lister-hooded rats (150–200 g)

Dosage:

0.1 mg/kg-0.3 mg/kg

Administration:

Subcutaneous injection; 0.1 mg/kg-0.3 mg/kg; single dose

Result:

Produced significantly greater hypothermia (at 0.3 mg/kg) than the saline group.

危险品运输编号 

UN 2811 6.1 / PGII

海关编码 

2937190000