中文名称:

奥美沙坦酯乙酯杂质

中文同义词:

奥美沙坦乙酯杂质;奥美沙坦酯乙酯杂质;奥美沙坦酯杂质U;美沙坦酯杂质U;奥美沙坦杂质19;奥美沙坦酯乙酯;美沙坦乙酯;雅脉膜衣锭乙酯杂质

英文名称:

OlMesartan Ethyl Ester IMpurity

英文同义词:

OlMesartan Ethyl Ester IMpurity;ethyl 1-((2-(1H-tetrazol-5-yl)-[1,1-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylate;Ethyl1-((2-(2H-tetrazol-5-yl)-[1,1-biphenyl]-4-yl)methyl)-4-(2-hydroxypropan-2-yl)-2-propyl-1H-imidazole-5-carboxylate;Ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[2-(1H-tetrazol-5-yl)biphenyl-4-yl]methyl-1H-imidazole-5-carboxylate;Olmesartan Medoxomil Impurity U;Olmesartan Medoxomil-12;Olmesartan Medoxomil impurity 10/Olmesartan Ethyl Ester/4-(2-Hydroxypropan-2-yl)-2-propyl-1-({4-[2-(2H-1,2,3,4-tetrazol-5-yl)phenyl]phenyl}methyl)-1H-imidazole-5-carboxylic acid ethyl ester;1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2-(2H-tetrazol-5-yl)[1,1-biphenyl]-4-yl]methyl]-, ethyl ester

CAS号:

144689-23-6

分子式:

C26H30N6O3

分子量:

474.55

EINECS号:

相关类别:

对照品-杂质对照品;杂质对照品

Mol文件:

144689-23-6.mol

沸点 

717.6±70.0 °C(Predicted)

密度 

1.26±0.1 g/cm3(Predicted)

酸度系数(pKa)

4.15±0.10(Predicted)

生物活性

Olmesartan ethyl ester (compound 11) 是Olmesartan 的一个杂质。Olmesartan (RNH-6270) 是血管紧张素II受体 (AT1R) 拮抗剂，可用于高血压研究。