中文名称:

细胞松驰素 E

中文同义词:

细胞松弛素E;细胞松驰素 E;松胞菌素E;松胞菌素 E 来源于棒曲霉;细胞松弛素 E 来源于棒曲霉;细胞松弛素;细胞松弛素E(>98%,BR)

英文名称:

CYTOCHALASIN E

英文同义词:

(7S,13E,16S,18R,19E)-6,7-Epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-21,23-dioxa[13]cytochalasa-13,19-diene-1,17,22-trione;[7β,13E,16S,18R,19E]-6,7-Epoxy-18-hydroxy-16,18-dimethyl-10-phenyl-21,23-dioxa[13]cytochalasa-13,19-diene-1,17,22-trione;(7s,13e,16s,18r,19e)-18-dimethyl-10-phenyl;21,23-dioxa(13)cytochalasa-13,19-diene-1,17,22-trione,6,7-epoxy-18-hydroxy-16,;6,7-epoxy-10-phenyl-5,6,16,18-tetramethyl-21,23-dioxa-[13]cytochalas-13,19-die;CYTOCHALASIN 3;CYTOCHALASIN E;CYTOCHALASIN E, ASPERGILLUS CLAVATUS

CAS号:

36011-19-5

分子式:

C28H33NO7

分子量:

495.56

EINECS号:

252-835-7

相关类别:

生化试剂;其他生化试剂;微生物代谢物;医药原料;antibiotic;Actin Inhibitors and ProbesCell Signaling and Neuroscience;Cell Signaling and Neuroscience;Cytoskeleton and Extracellular Matrix;Mold;Toxins and Venoms

Mol文件:

36011-19-5.mol

熔点 

206 °C

沸点 

587.59°C (rough estimate)

密度 

1.2415 (rough estimate)

折射率 

1.6290 (estimate)

储存条件 

-20°C

形态

White solid.

BRN 

1096975

生物活性

Cytochalasin E 是一种含有曲霉衍生真菌代谢产物的环氧化物，抑制血管生成和肿瘤生长，Cytochalasin E 是一种有效的肌动蛋白解聚剂，能结合肌动蛋白丝的倒刺端并盖住，以防止肌动蛋白伸长。

体外研究

Cytochalasin E prominently inhibits the growth of A549 cells in a dose-dependent manner. Cytochalasin E could induce the up-regulation of autophagy-related protein (LC3-II) and SQSTM1/p62.

危险品标志 

T+,T

危险类别码 

26/27/28-63

安全说明 

28-36/37-45

危险品运输编号 

UN 1544 6.1/PG 2

WGK Germany 

3

RTECS号

HA5360000

F 

10

HazardClass 

6.1(a)

PackingGroup 

I

海关编码 

29349990