中文名称:

2-O-甲基腺苷

中文同义词:

2-O-甲基腺嘌呤核苷;2‘-甲氧基腺苷;2-O-甲基腺苷;2-甲氧基腺;2-甲氧基腺苷, 99.0%;甲氧基腺苷;2-甲氧基腺苷(2-OME-RA)

英文名称:

2-O-Methyladenosine

英文同义词:

2-OMe-rA;2-O-Methyladenosine, 99.0%;2-O-Me-Ado;-O-Methyladenosine;2-Amino-N6-(dimethylaminomethylidene)-N2-isobutyryl-2rsquo;AMI;2-O-Methyladdenosine;(2R,3R,4R,5R)-5-(6-AMino-9H-purin-9-yl)-2-(hydroxyMethyl)-4-Methoxytetrahydrofuran-3-ol

CAS号:

2140-79-6

分子式:

C11H15N5O4

分子量:

281.27

EINECS号:

1308068-626-2

相关类别:

核酸;核苷;生化试剂;核苷，核苷酸，寡核苷酸;陕西林奈主打产品;Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides;Bases Related Reagents;Carbohydrates Derivatives;Heterocycles;Nucleotides

Mol文件:

2140-79-6.mol

熔点 

200-202 C

沸点 

623.8±65.0 °C(Predicted)

密度 

1.84±0.1 g/cm3(Predicted)

储存条件 

Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

酸度系数(pKa)

13.13±0.70(Predicted)

形态

Powder

颜色

White to Off-white

水溶解性 

Soluble in water.

最大波长(λmax)

259nm(H2O)(lit.)

InChIKey

FPUGCISOLXNPPC-YGHVBYMHSA-N

CAS 数据库

2140-79-6(CAS DataBase Reference)

生物活性

2-O-Methyladenosine 是甲基化腺嘌呤的残基，在正常人群和腺苷脱氨基酶(ADA) 的尿液中可被检测到。2-O-Methyladenosine 具有独特的降血压活性。

靶点

Human Endogenous Metabolite

Human Endogenous Metabolite

体内研究

2-O-Methyladenosine (100, 200 mg/kg, ip, single dose) exhibits unique hypotensive activities in rats. Animal Model: Male spontaneously hypertensive rats (SHR; 16 weeks old). Dosage: 100, 200 mg/kg. Administration: IP, single dose. Result: Exhibited a significant hypotensive effect in decreasing blood pressure by about 40-50%.

Animal Model:

Male spontaneously hypertensive rats (SHR; 16 weeks old).

Dosage:

100, 200 mg/kg.

Administration:

IP, single dose.

Result:

Exhibited a significant hypotensive effect in decreasing blood pressure by about 40-50%.

用途 

贮存温度: -20°C

危险品标志 

Xi

危险类别码 

36/37/38

安全说明 

26-36-24/25

WGK Germany 

3

海关编码 

29349990