中文名称:

1,3,5,8-四羟基-2,4-双(3-甲基-2-丁烯基)-9H-氧杂蒽-9-酮

中文同义词:

1,3,5,8-四羟基-2,4-双(3-甲基-2-丁烯基)-9H-氧杂蒽…;藤黄苷;藤黄苷, 来源于山竹果;1,3,5,8-四羟基-2,4-双(3-甲基-2-丁烯基)-9H-氧杂蒽-9-酮;藤黄素

英文名称:

1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-9H-xanthen-9-one

英文同义词:

1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-9h-xanthen-9-one;gartanin;1,3,5,8-Tetrahydroxy-2,4-bis(3-methyl-2-butenyl)xanthone;9H-Xanthen-9-one, 1,3,5,8-tetrahydroxy-2,4-bis(3-methyl-2-butenyl)-;Aids098106;Aids-098106;1,3,5,8-Tetrahydroxy-2,4-bis(3-methylbut-2-en-1-yl)-9H-xanthen-9-one;Gartanin, 98%, from Garcinia mangostana L.

CAS号:

33390-42-0

分子式:

C23H24O6

分子量:

396.43

EINECS号:

相关类别:

标准品;植物提取物;分析试剂标准品;对照品;氧杂蒽酮;标准品 -中药标准品

Mol文件:

33390-42-0.mol

熔点 

167℃

沸点 

644.4±55.0 °C(Predicted)

密度 

1.326±0.06 g/cm3(Predicted)

酸度系数(pKa)

7.17±0.20(Predicted)

生物活性

Gartanin 是山竹果中的天然黄酮，具有抗氧化、抗炎、抗真菌、神经保护和抗肿瘤作用。在人脑胶质瘤细胞中，Gartanin 诱导细胞周期阻滞和自噬，抑制其迁移。

体外研究

Gartanin is a potential agent against glutamate-induced oxidative injury partially through increasing Nrf-2-independed HO-1 and AMPK/SIRT1/PGC-1α signaling pathways . Gartanin induces cell cycle arrest and autophagy and suppresses migration involving PI3K/Akt/mTOR and MAPK signalling pathway in human glioma cells .