磷酸三(1,3-二氯异丙基)酯
中文名称:
磷酸三(1,3-二氯异丙基)酯
中文同义词:
磷酸三(1,3-二氯-2-丙基)酯溶液,100PPM;TRIS(1,3-DICHLORO-2-PROPYL) PHOSPHATE 磷酸三(1,3-二氯-2-丙基)酯;磷酸三(1,3-二氯-2-丙基)酯;磷酸三(1,3-二氯异丙基)酯;磷酸三(1,3-二氯异丙基)酯(TDCPP);磷酸三(1.3-二氯-2-丙基)酯;三(1,3-二氯异丙基)磷酸酯;三(1,3-二氯-2-丙基)磷酸酯
英文名称:
Tris(1,3-dichloro-2-propyl)phosphate
英文同义词:
1,3-Dichloro-2-propanol phosphate, Phosphoric acid tris(1,3-dichloro-2-propyl ester);1,3-Dichloro-2-propanol phosphate, Phosphoric acid tris(1,3-dichloro-2-propyl ester), Tris(1,3-dichloro-2-propyl) phosphate;Tris(1,3-Dichloro-2-Propyl)Phosphate(TDPP);Phosphoric acid tris(1,3-dichloropropan-2-yl;Phosphoric acid tris(1,3-dichloropropan-2-yl) ester;Tris(1,3-dichloropropane-2-yl) phosphate;1,3-Dichloro-2-propanol phosphate;tris(1,3-dichloropropan-2-yl) phosphate
CAS号:
13674-87-8
分子式:
C9H15Cl6O4P
分子量:
430.9
EINECS号:
237-159-2
相关类别:
该产品具有高效阻燃剂，挥发性低，热稳定性高，耐水，耐碱稳定易溶于多数有机物质，加工性能好，用塑，防潮，防静电，防拉，防压缩性能。广泛用于不饱和聚酯，聚氨酯泡沫塑料，环氧树脂，酚醛树;电子材料;磷酸酯阻燃剂;塑料及制品;塑料阻燃剂;阻燃剂;Organics;Functional Materials;Phosphates (Plasticizer);Plasticizer;磷化合物;医药中间体;除草剂;有机化工原料
Mol文件:
13674-87-8.mol
熔点
-64°C
沸点
315°C
密度
1.512
折射率
n20/D 1.503
闪点
249°C
形态
solid
比重
1.518 (20/4℃)
水溶解性
<0.1 g/100 mL at 24 ºC
Decomposition
240-280 ºC
Merck
14,9087
稳定性
Stable. Reacts slowly with aqueous acids and alkalies. May soften plastics.
InChIKey
ASLWPAWFJZFCKF-UHFFFAOYSA-N
CAS 数据库
13674-87-8(CAS DataBase Reference)
NIST化学物质信息
Tris(1,3-dichloroisopropyl)phosphate(13674-87-8)
EPA化学物质信息
Tris(1,3-dichloro-2-propyl)phosphate (13674-87-8)
生物活性
TDCPP 是三 (2,3-二溴丙基) 磷酸酯 (Tris) 的氯化类似物，它是在环境中检测到的最多的有机磷阻燃剂 (OPFR) 之一。
体外研究
Exposure to TDCPP does not significantly affect cell viability until at concentration >68 μg/mL. HCECs show a 16% cell viability loss after exposing to 136 μg/mL TDCPP. Moreover, TDCPP induces a sharp decrease in viable cells (87%) after exposing to ≥272 μg/mL TDCPP. Based on cell viability, the LC 50 value for TDCPP is 202 μg/mL using a nonlinear regression. Compare to controls, TDCPP-exposed cells exhibit a concentration-dependent increase in apoptosis. Anti-apoptotic Bcl-2 protein expression is increased to 1.4 fold after exposing to 2 μg/mL TDCPP, 1.2-folds at 20 μg/mL but dynamically decreased to 0.4 fold at 200 μg/mL compare to control. The caspase-3 activity is increased to 2.1 folds of the control at 200 μg/mL TDCPP. TDCPP inhibits cell growth at lower concentrations (IC 50 of 27 μM), while cell viability and toxicity are affected at higher concentrations (IC 50 of 171 μM and 168 μM, respectively).
用途
应用于矿用运输带、电缆、电器、壁纸、皮革等行业
危险品标志
Xn,N
危险类别码
20/21/22-36/37/38-51/53-38-20-40
安全说明
26-36/37/39-61-36/37
危险品运输编号
UN 3082 9/PG 3
WGK Germany
2
RTECS号
UB1473000
HazardClass
9
PackingGroup
III
海关编码
29199000
毒害物质数据
13674-87-8(Hazardous Substances Data)
毒性
LD50 orally in rats: 1.85 g/kg (Piotrowski)
