中文名称:

洋槐黄素

中文同义词:

洋槐黄素;洋槐黄素标准品;洋槐黄素对照品

英文名称:

ROBINETIN

英文同义词:

ROBINETIN;3,3’,4’,5’,7-pentahydroxy-flavon;3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4h-1-benzopyran-4-on;norkanugin;3,7,3,4,5-PENTAHYDROXYFLAVONE;5-HYDROXYFISETIN;3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)-4-benzopyrone;3,7-dihydroxy-2-(3,4,5-trihydroxyphenyl-4H-1-benzopyran-4-one) (Robinetin)

CAS号:

490-31-3

分子式:

C15H10O7

分子量:

302.24

EINECS号:

207-709-6

相关类别:

植物提取物;黄酮;标准品 -中药标准品;标准品，对照品;对照品;Flavanols;Penta-substituted Flavones

Mol文件:

490-31-3.mol

熔点 

326-328°C

沸点 

363.28°C (rough estimate)

密度 

1.3616 (rough estimate)

折射率 

1.4790 (estimate)

储存条件 

Sealed in dry,2-8°C

酸度系数(pKa)

6.82±0.40(Predicted)

生物活性

Robinetin (3,3,4,5,7-Pentahydroxyflavone) 是一种天然黄酮，具有显着的“两种颜色”固有荧光特性，具有抗真菌、抗病毒、抗菌、抗突变和抗氧化活性。Robinetin 还可以抑制脂质过氧化和蛋白质糖基化。

体外研究

Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner. Robinetin inhibits the DNA synthesis in Proteus vulgaris , and the RNA synthesis in S. aureus . Robinetin (100-200 or 25 μM; 1 or 72 h) inhibits egg yolk phosphatidylcholine (EYPC) membrane lipid peroxidation and hemoglobin A (HbA) glycosylation with high efficiency. Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore.

危险类别码 

22

安全说明 

22-45

危险品运输编号 

2811