中文名称:

丙半胱氨酸

中文同义词:

R (-)-2 -氧代噻唑啉-4-羧酸;(R)-2-氧代噻唑烷-4-羧酸;L-2-氧硫杂唑烷-4-羧酸;丙半胱氨酸;氧代噻唑烷羧酸;R-(-)-2-氧代噻唑啉-4-羧酸;L-2-噻唑林二酮-4-甲酸;L-2-噻唑林二酮-4-甲酸/丙半胱氨酸

英文名称:

Procysteine

英文同义词:

(4R)-2-Oxothiazolidine-4-carboxylic acid;(4R)-2-Oxothiazolidine-4α-carboxylic acid;L-2-Thiazolidinone-4-carboxylic Acid,L-2-Oxothiazolidine-4-carboxylic Acid;(4R)-2-ketothiazolidine-4-carboxylic acid;L-Thiazolidin-2-one-4-carboxylic acid, OTC, Procysteine, OTZ;Oxothiazolidine carboxylate;4-Thiazolidinecarboxylicacid, 2-oxo-, (4R)-;L-2-Thiazolidinone-4-carboxylic Acid

CAS号:

19771-63-2

分子式:

C4H5NO3S

分子量:

147.15

EINECS号:

200-154-8

相关类别:

非天然氨基酸衍生物;化工中间体;化工原料-1827181813;日化原料;化妆品类;主打产品;陕西林奈主打产品;CARBOXYLICACID;whitening and anti-aging material and other functions in cosmetics;化妆品原料;医药原料

Mol文件:

19771-63-2.mol

熔点 

174 °C (dec.)(lit.)

比旋光度 

-60 º (c=1 in H2O)

密度 

1.582±0.06 g/cm3(Predicted)

折射率 

-64 ° (C=1, H2O)

储存条件 

Keep in dark place,Sealed in dry,Room Temperature

形态

Powder

酸度系数(pKa)

pKa (22°): 3.32

颜色

White to Off-white

水溶解性 

Soluble in water

Merck 

13,7019

BRN 

4179169

CAS 数据库

19771-63-2(CAS DataBase Reference)

生物活性

Oxothiazolidinecarboxylic acid 是一种抗氧化剂，是半胱氨酸的前药，它是惰性的，在细胞内代谢成半胱氨酸，从而刺激谷胱甘肽的合成。

体内研究

Oxothiazolidinecarboxylic acid treatment attenuates plantaris atrophy, restored glutathione levels, and increased catalase, Cu/Zn-SOD1, and Mn-SOD2 mRNA expression, but did not reduce other markers of oxidant stress or levels of these catabolic factors. Animal Model: Male Sprague-Dawley rats (200-250 g, n= 6-7 rats/group). Dosage: 0.35% (w/v). Administration: Added to their diets at a concentration of 0.35% (w/v) for the final 12 wk. Result: Increased fiber CSAs compared to the non-supplemented, alcohol-fed group.

Animal Model:

Male Sprague-Dawley rats (200-250 g, n= 6-7 rats/group).

Dosage:

0.35% (w/v).

Administration:

Added to their diets at a concentration of 0.35% (w/v) for the final 12 wk.

Result:

Increased fiber CSAs compared to the non-supplemented, alcohol-fed group.

危险品标志 

Xi

危险类别码 

36/37/38

安全说明 

26-36

WGK Germany 

3

RTECS号

XJ5426650