中文名称:

5-脱氧-5-甲硫腺苷

中文同义词:

5-甲硫腺苷;5-脱氧-5-硫代甲基酰苷;5-脱氧-5-甲硫腺苷;5ˊ-脱氧-5ˊ-甲硫基腺苷;甲硫腺苷;5′-脱氧-5′-腺苷;5-脱氧-5-甲硫腺苷 (5-脱氧-5-硫代甲基酰苷、5ˊ-脱氧-5ˊ-甲硫基腺苷);甲硫腺苷对照品

英文名称:

5-DEOXY-5-METHYLTHIOADENOSINE

英文同义词:

2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol;7-(5-Methylthio-5-deoxy-D-ribofuranosyl)-7H-purine-6-amine;7-[Tetrahydro-3α,4α-dihydroxy-5β-(methylthiomethyl)furan-2-yl]-7H-purin-6-amine;5-S-Methyl-5-thioadesine;5-Deoxy-5-(methylthio)adenosine ,98%;1-(6-AMino-9H-purin;5-Deoxy(Methylthio)adenosine;NSC 335422

CAS号:

2457-80-9

分子式:

C11H15N5O3S

分子量:

297.33

EINECS号:

相关类别:

中药对照品;生物碱;化工原料;Biochemicals and Reagents;Nucleoside Analogs;Nucleosides, Nucleotides, Oligonucleotides

Mol文件:

2457-80-9.mol

熔点 

210-213 °C (dec.)

沸点 

642.7±65.0 °C(Predicted)

密度 

1.85±0.1 g/cm3(Predicted)

储存条件 

-20°C

酸度系数(pKa)

13.10±0.70(Predicted)

形态

White solid

BRN 

42420

生物活性

5-Methylthioadenosine 是由 S-腺苷酸产生的，有强效的抑制作用。

靶点

Human Endogenous Metabolite

Human Endogenous Metabolite

体外研究

5-Methylthioadenosine (MTA) can affect cellular processes in many ways. 5-Methylthioadenosine has been shown to influence numerous critical responses of the cell including regulation of gene expression, proliferation, differentiation and apoptosis. Although most of these responses have been observed at the pharmacological level, their specificity makes it tempting to speculate that endogenous 5-Methylthioadenosine could play a regulatory role in the cell. Finally, observations carried out in models of liver damage and cancer demonstrate a therapeutic potential for 5-Methylthioadenosine that deserves further consideration [1] .

安全说明 

22-24/25

WGK Germany 

3

RTECS号

AU7410000

F 

10-21