一水没食子酸
中文名称:
一水没食子酸
中文同义词:
没食子酸 一水合物;没食子酸一水化合物;没食子酸,一水物(分析标准品,>99%(HPLC));没食子酸单水合物, ACS级;电子级没食子酸;没食子酸,一水物,AR,98.5%;没食子酸水合物;3,4,5-三羟基苯甲酸一水化物,99%
英文名称:
Gallic acid monohydrate
英文同义词:
Gallic Acid, Monohydrate, Crystal, Reagent, ACS;Gallic acid monohydrate >=99% (HPLC);Gallic acid monohydrate ACS reagent, >=98.0%;Gallic acid monohydrate Vetec(TM) reagent grade, 98%;Benzoic acid,3,4,5-trihydroxy-, hydrate (1:1);GALLIC ACID-1-HYDRATE;GALLIC ACID MONOHYDRATE;GALLIC ACID, HYDRATE
CAS号:
5995-86-8
分子式:
C7H8O6
分子量:
188.13
EINECS号:
611-919-7
相关类别:
羰基化合物;有机化工;医药中间体;通用试剂;分析标准品;医用原料;无机盐;Pharmaceutical Intermediates;Antioxidant;有机酸;食品和饮料标准品;羧酸;工业原料;化学试剂;植物提取物;生化试剂-其他化学试剂;化工;一水没食子酸;无机盐;原料;添加剂;Biochemistry;ACS Grade;Building Blocks;C7;Carbonyl Compounds;Carboxylic Acids;Chemical Synthesis;Essential Chemicals;Inorganic Salts;Organic Building Blocks;Research Essentials;Solutions and Reagents;Myrica cerifera;Acacia;Aspalathus linearis (Rooibos tea);Cimicifuga racemosa;Ephedra sinica;Euphorbia sp;Hypericum perforatum (St John′;Nutrition Research;Phytochemicals by Plant (Food/Spice/Herb);s wort);Vaccinium myrtillus (Bilberry)
Mol文件:
5995-86-8.mol
熔点
252 °C (dec.)(lit.)
密度
1.694
闪点
250 °C
储存条件
Keep in dark place,Sealed in dry,Room Temperature
溶解度
It is soluble in alcohol, ether, glycerol, acetone negligible in benzene, chloroform, petroleum ether.
形态
Solid
颜色
White to cream
水溶解性
15 g/l (20 ºC)
敏感性
Hygroscopic
Merck
14,4345
BRN
2050274
InChIKey
IUTKPPDDLYYMBE-UHFFFAOYSA-N
CAS 数据库
5995-86-8(CAS DataBase Reference)
生物活性
Gallic acid (3,4,5-Trihydroxybenzoic acid) hydrate 是一种天然多羟基酚类化合物，具有抑制环氧合酶-2 (COX-2) 的自由基清除作用。Gallic acid hydrate 具有多种活性，如抗菌、抗氧化、抗菌、抗炎和抗肿瘤活性。
靶点
COX-2
Human Endogenous Metabolite
COX-2
Human Endogenous Metabolite
体外研究
Gallic acid is an antioxidant which can inhibit both COX-2. After 18 h treatment with Gallic acid, the number of viable neutrophils is dramatically decreased from 40.3% to 27.7%, highly comparable with 26.4% for untreated neutrophils. Gallic acid fails to attenuate isoproterenol-induced myocytolysis.
体内研究
The food intake (2.6±0.08 g/day, p=0.69) and the body weight (2.5±0.69 g, p=0.76) of the Gallic acid group do not differ significantly from those of the control group (food intake; 2.41±0.14 g/day and the body weight; 2.83±0.84 g/day). The blood glucose tolerance in the Gallic acid group is significantly improved after 2 weeks of treatment. The blood glucose tolerance of the Gallic acid group after a treatment period of 2 weeks is also significantly better than that of the control group at 90 and 120 min ( p<0.05). The serum triglyceride concentration in the Gallic acid group (0.67±0.03 mM, p<0.05) is significantly reduced relative to that of the control group (1.08±0.20 mM). The total cholesterol concentration is similar in the control (3.19±0.27 mM) and Gallic acid (3.01±0.18 mM) groups.
化学性质
白色或淡黄色针状晶体，或棱柱状晶体。有绢丝光泽，味微酸。 溶于乙醇、丙酮、乙二醇，微溶于水、乙醚。
用途
用于制造噻嗪染料、恶嗪染料、药物等
用途
用作电化分析中的去极剂；用于还原磷钼酸；用于检定锑、钡、铋、钙、铈和铜等；用于测定磷、亚硝酸盐、银、钍和钛等
用途
试验游离矿酸、二羟基丙酮和生物碱等，电化分析中的去极剂，还原磷钼酸，检定锑、钡、铋、钙、铈和铜等。测定磷、亚硝酸盐、银、钍和钛等。
类别
有毒物质
毒性分级
中毒
急性毒性
静脉-小鼠 LD50: 320 毫克/公斤
可燃性危险特性
可燃, 火场排出辛辣刺激烟雾
储运特性
库房低温, 通风, 干燥
灭火剂
水, 二氧化碳, 干粉, 砂土
危险品标志
Xi
危险类别码
36/37/38
安全说明
26-36-24/25
WGK Germany
2
RTECS号
LW7525000
F
8-9-23
TSCA
Yes
海关编码
29182900
