中文名称:

益多酯

中文同义词:

多利脂;乙羟茶碱安妥明酯;益多酯;益多酯/乙羟茶碱安妥明酯

英文名称:

ETOFYLLINE CLOFIBRATE

英文同义词:

ETOFYLLINE CLOFIBRATE;1-(7-theophyllinyl)-2-ethyl(2-(p-chlorophenoxy)isobutyrate);1-(theophyllin-7-yl)-aethyl-22-(p-chlorphenoxy)-2-methylpropionat;1-(theophyllin-7-yl)-ethyl-22-(p-chlorophenoxy)-2-methylpropionate;duolip;etofyllinclofibrat;etofyllinclofibrate;ml1024

CAS号:

54504-70-0

分子式:

C19H21ClN4O5

分子量:

420.85

EINECS号:

259-191-6

相关类别:

API

Mol文件:

54504-70-0.mol

熔点 

133-135°

密度 

1.3758 (rough estimate)

折射率 

1.6500 (estimate)

CAS 数据库

54504-70-0

生物活性

Etofylline clofibrate 具有降脂和抗血栓形成作用。Etofylline clofibrate 具有与内膜 PGI2 激动的相互作用。

体内研究

Etofylline clofibrate (p.o.; 12 mg/kg) has the moderate effect of a single dose (12% reduction in disaggregation time) and has a maximum reduction of 31 and 43% following 5 and 7 consecutive daily applications, respectively.

用途 

降血脂药。

毒性

LD50 in mice, rats, dogs (g/kg): 11.7, 17.0, >10.0 orally (Metz et al.)